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The immunoreceptor tyrosine-based inhibition motif (ITIM)-containing receptor G6b-B is critical for platelet production and… Expand Unlike primary myelofibrosis (PMF) in adults, myelofibrosis in children is rare. Congenital (inherited) forms of myelofibrosis… Expand The immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing receptor G6b-B has emerged as a key regulator of platelet… Expand An inhibitory receptor ensures that megakaryocytes produce proper numbers of functional platelets. Controlling Platelet… Expand Platelet activation is regulated by both positive and negative signals. G6B-b is an inhibitory platelet receptor with an… Expand Platelets play an essential role in wound healing by forming thrombi that plug holes in the walls of damaged blood vessels. To… Expand The G6b-B gene encodes a novel cell surface receptor of the immunoglobulin superfamily that activates inhibitory signaling… Expand