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G207

A neuroattenuated, replication-competent, recombinant herpes simplex virus-1 (HSV-1) with potential oncolytic activity. Upon intracerebral… 
National Institutes of Health

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Related topics

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NCIt Antineoplastic Agent Terminology

Papers overview

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Highly Cited
2005
Highly Cited
2005
Engineered biosynthesis of plant polyketides: chain length control in an octaketide-producing plant type III polyketide synthase.
The chalcone synthase (CHS) superfamily of type III polyketide synthases (PKSs) produces a variety of plant secondary metabolites… 
Highly Cited
2002
Highly Cited
2002
Comparison of safety, delivery, and efficacy of two oncolytic herpes viruses (G207 and NV1020) for peritoneal cancer
G207 and NV1020 are two replication-competent, multimutant oncolytic herpes simplex viruses evaluated in the current studies for… 
Highly Cited
2001
Highly Cited
2001
Intravesical oncolytic viral therapy using attenuated, replication‐competent, herpes simplex viruses G207 and Nv1020 is effective in the treatment of bladder cancer in an orthotopic syngeneic model
Attenuated, replication‐competent herpes simplex virus mutants are attracting interest because of their ability to replicate… 
Highly Cited
2000
Highly Cited
2000
Viral shedding and biodistribution of G207, a multimutated, conditionally replicating herpes simplex virus type 1, after intracerebral inoculation in aotus.
G207 is a multimutated, conditionally replicating herpes simplex virus type 1 (HSV-1) that is currently in clinical trial for… 
Highly Cited
2000
Highly Cited
2000
Effective treatment of pancreatic tumors with two multimutated herpes simplex oncolytic viruses
Highly Cited
1999
Highly Cited
1999
Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation of Intracerebral Injection in Nonhuman Primates
ABSTRACT This study examined the safety of intracerebral inoculation of G207, an attenuated, replication-competent herpes simplex… 
Highly Cited
1999
Highly Cited
1999
Local and systemic therapy of human prostate adenocarcinoma with the conditionally replicating herpes simplex virus vector G207.
Prostate adenocarcinoma is the most common nonskin malignancy in males and the second most common cause of cancer death in the… 
Highly Cited
1999
Highly Cited
1999
Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma.
Replication-competent virus vectors are attractive therapeutic agents for cancer. G207, a second-generation, multimutated herpes… 
Highly Cited
1998
Highly Cited
1998
Treatment of human breast cancer in a brain metastatic model by G207, a replication-competent multimutated herpes simplex virus 1.
We investigated the therapeutic efficacy of G207, a replication-competent multimutated herpes simplex virus type 1, for the… 
Highly Cited
1995
Highly Cited
1995
Treatment of human malignant meningiomas by G207, a replication-competent multimutated herpes simplex virus 1.
We have demonstrated that replication-competent attenuated mutants of herpes simplex virus type 1 (HSV-1) have therapeutic… 
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