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Fumagillin-Derived Polymer Conjugate XMT-1107

Known as: XMT-1107 
A polymeric prodrug consisting of the fumagillol-derived small molecule XMT-1191 tethered to the hydrophilic, biodegradable70 kDa polymer poly[1… Expand
National Institutes of Health

Papers overview

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2014
2014
2526 Background: Fumagillol derivatives are novel anti-angiogenic agents that inhibit methionine aminopeptidase 2 (MetAP2) rather… Expand
2010
2010
Teva Pharmaceutical Industries has entered into an agreement with Mersana Therapeutics for rights to develop and commercialize… Expand
2010
2010
XMT-1107 is a novel polymer fumagillol derivative, comprised of the small molecule XMT-1191 conjugated to a 70 kDa biodegradable… Expand
2009
2009
XMT-1107, a fumagillin-derived polymer conjugate, and XMT-1191, the in vivo release product of XMT-1107, were evaluated for (1… Expand
2009
2009
XMT-1107 is a novel polymer fumagillol derivative, comprised of the small molecule XMT-1191 conjugated to a 70 kDa biodegradable… Expand