FAQ

Free Immunoglobulin Light Chain

Known as: FLK, Free Light Chain, Immunoglobulin light chains.free 
Immunoglobulin kappa and/or lambda light chains that are not bound to immunoglobulin heavy chains. These proteins are produced in vivo by B-cells but… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
0102019692017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Evaluation of demographic history and neutral parameterization on the performance of FST outlier tests
F(ST) outlier tests are a potentially powerful way to detect genetic loci under spatially divergent selection. Unfortunately, the… (More)
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2013
2013
Serum free light chain ratio as a biomarker for high-risk smoldering multiple myeloma
A markedly elevated serum free light chain (FLC) ratio may serve as a biomarker for malignant transformation in high-risk… (More)
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Highly Cited
2010
Highly Cited
2010
Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing.
Protein arginine methylation, one of the most abundant and important posttranslational modifications, is involved in a multitude… (More)
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2008
2008
Appraisal of immunoglobulin free light chain as a marker of response.
The immunoglobulin free light chain (FLC) assay is an invaluable tool for following patients with oligosecretory plasma cell… (More)
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2008
2008
Evaluation of the serum-free light chain test in untreated patients with AL amyloidosis.
We evaluated the Serum Free Light Chain (FLC) test in a series of 133 untreated patients with systemic AL amyloidosis. The FLC… (More)
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2006
2006
Immunoglobulin free light chains and solitary plasmacytoma of bone.
An abnormal serum immunoglobulin free light chain (FLC) ratio at diagnosis may identify risk of progression to myeloma in… (More)
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Highly Cited
2006
Highly Cited
2006
Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation.
The immunoglobulin free light chain (FLC) is the precursor protein of amyloid in primary systemic amyloidosis (AL). Historically… (More)
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Highly Cited
2004
Highly Cited
2004
A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C.
Posttranscriptional RNA metabolism plays versatile roles in the regulation of gene expression during eukaryotic growth and… (More)
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Highly Cited
2004
Highly Cited
2004
Regulation of flowering time in Arabidopsis by K homology domain proteins.
The transition from vegetative growth to reproductive development in Arabidopsis is regulated by multiple floral induction… (More)
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Highly Cited
1996
Highly Cited
1996
Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain.
Vascular endothelial growth factor (VEGF), a potent angiogenic factor, uses two receptor tyrosine kinases, FLK/KDR and FLT, to… (More)
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