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Free Immunoglobulin Light Chain

Known as: FLK, Free Light Chain, Immunoglobulin light chains.free 
Immunoglobulin kappa and/or lambda light chains that are not bound to immunoglobulin heavy chains. These proteins are produced in vivo by B-cells but… 
National Institutes of Health

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Related topics

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Immunoglobulin light chains.free:MRat:24H:Urine:Qn

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Multiple sclerosis: assay of free immunoglobulin light chains
Over the past five years, a number of papers have appeared describing the assay of free immunoglobulin light chains in… 
Review
2012
Review
2012
Extended use of serum free light chain as a biomarker in lymphoproliferative disorders: a comprehensive review.
Serum free light chain (sFLC) assays were shown to improve detection, management, and prognostication in plasma cell disorders… 
Highly Cited
2007
Highly Cited
2007
Immunohistochemical analysis of growth mechanisms in juvenile nasopharyngeal angiofibroma
Angiogenic factors are discussed to participate in growth and promotion of juvenile nasopharyngeal angiofibroma (JNA). However… 
Review
2006
Review
2006
Immunochemical quantification of free immunoglobulin light chains from an analytical perspective
Abstract Immunoglobulin light chains are components of antibodies, but some exist in a free form in serum and urine as a result… 
Review
2006
Review
2006
Assessment of serum free light chain assays for plasma cell disorder screening in a Veterans Affairs population.
This study evaluated serum kappa and lambda free light chain (FLC) concentrations in a Veterans Affairs (VA) population. We… 
2004
2004
Flavoenzyme-catalyzed redox cycling of hydroxylamino- and amino metabolites of 2,4,6-trinitrotoluene: implications for their cytotoxicity.
Highly Cited
2003
Highly Cited
2003
SU 11248 Inhibits KIT and Platelet-derived Growth Factor Receptor in Preclinical Models of Human Small Cell Lung Cancer
The purpose of this study was to evaluate the activity of the indolinone kinase inhibitor SU11248 against the receptor tyrosine… 
Highly Cited
1997
Highly Cited
1997
Nitrobenzimidazoles as substrates for DT-diaphorase and redox cycling compounds: their enzymatic reactions and cytotoxicity.
We have synthesized a number of nitrobenzimidazoles containing nitro groups in the benzene ring and found that they acted as… 
1991
1991
Immunoturbidimetric assay for estimating free light chains of immunoglobulins in urine and serum.
An immunoturbidimetric assay for the assessment of free kappa and lambda light chains of immunoglobulins was developed using a… 
1978
1978
Free immunoglobulin light chain synthesis by neoplastic cells in leukaemic reticuloendotheliosis.
Neoplastic cell preparations from four patients with clinically and morphologically well-defined leukaemic reticuloendotheliosis… 
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