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Formazans

Known as: Formazans [Chemical/Ingredient] 
Colored azo compounds formed by the reduction of tetrazolium salts. Employing this reaction, oxidoreductase activity can be determined quantitatively… Expand
National Institutes of Health

Related topics

Related topics

8 relations

Narrower (4)

1,3,5-triphenylformazan1,5-diphenylformazanMTT formazannitroblue formazan

Broader (1)

Indicators and Reagents
aspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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Review
2018
Review
2018
Tetrazolium salts and formazan products in Cell Biology: Viability assessment, fluorescence imaging, and labeling perspectives.
For many years various tetrazolium salts and their formazan products have been employed in histochemistry and for assessing cell… Expand
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Highly Cited
2007
Highly Cited
2007
Formazans as beta-diketiminate analogues. Structural characterization of boratatetrazines and their reduction to borataverdazyl radical anions.
Formazans react with boron triacetate to produce boratatetrazines, which can be reduced to yield borataverdazyl radical anions… Expand
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Review
2005
Review
2005
Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction.
Tetrazolium salts have become some of the most widely used tools in cell biology for measuring the metabolic activity of cells… Expand
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Highly Cited
2005
Highly Cited
2005
The measurement in tissue sections of the two formazans derived from Nitroblue Tetrazolium in dehydrogenase reactions
  • R. Butcher
  • The Histochemical Journal
  • 2005
    • Corpus ID: 44564195
The activity of dehydrogenases in tissue sections can at present be quantified by scanning and integrating microdensitometry… Expand
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Highly Cited
2002
Highly Cited
2002
Mitochondrial and nonmitochondrial reduction of MTT: interaction of MTT with TMRE, JC-1, and NAO mitochondrial fluorescent probes.
BACKGROUND Bioreduction of water-soluble tetrazolium salts (e.g., MTS, XTT, and MTT) to their respective formazans is generally… Expand
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Highly Cited
1999
Highly Cited
1999
Spectrophotometric Assay for Superoxide Dismutase Based on the Reduction of Highly Water-soluble Tetrazolium Salts by Xanthine-Xanthine Oxidase.
Two novel highly water-soluble tetrazolium salts, WST-1 (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene… Expand
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Highly Cited
1986
Highly Cited
1986
Consequences of cadmium toxicity in rat hepatocytes: mitochondrial dysfunction and lipid peroxidation.
Cadmium (Cd) (10-100 microM) decreased the ATP/ADP ratio and enhanced lipid peroxidation (LPO) (measured as thiobarbituric acid… Expand
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Review
1976
Review
1976
Tetrazolium salts and formazans.
  • F. Altman
  • Progress in histochemistry and cytochemistry
  • 1976
    • Corpus ID: 146976
The history of the tetrazolium salts and formazans goes back 100 years, to when Friese (1875) reacted benzene diazonium nitrate… Expand
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Highly Cited
1972
Highly Cited
1972
NONOSMIOPHILIC TETRAZOLIUM SALTS THAT YIELD OSMIOPHILIC, LIPOPHOBIC FORMAZANS FOR ULTRASTRUCTURAL LOCALIZATION OF DEHYDROGENASE ACTIVITY
Monotetrazolium salts were designed and prepared which incorporate a phthalhydrazide moiety to make them lipophobic and a… Expand
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Highly Cited
1957
Highly Cited
1957
INTRACELLULAR LOCALISATION OF DEHYDROGENASE SYSTEMS USING MONOTETRAZOLIUM SALTS AND METAL CHELATION OF THEIR FORMAZANS
  • A. G. Pearse
  • The journal of histochemistry and cytochemistry…
  • 1957
    • Corpus ID: 36261738
1) A method is proposed for the demonstrations of dehydrogenases and diaphorases using the principle of simultaneous chelation of… Expand
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