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Flavoxate

Known as: 2-Piperidinoethyl 3-methylflavone-8-carboxylate, 4H-1-Benzopyran-8-carboxylic acid, 3-methyl-4-oxo-2-phenyl-, 2-(1-piperidinyl)ethyl ester, 2-(1-Piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate 
A synthetic parasympatholytic with antimuscarinic, muscle relaxant and urinary antispasmodic properties. Flavoxate binds and inhibits muscarinic… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (6)

3-methylflavone-8-carboxylic acidFlavoxate HydrochlorideSpasuretUrispas
Esophageal AchalasiaGastric outlet obstructionGastrointestinal HemorrhageIn Blood

Broader (2)

ParasympatholyticsUrological Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2002
Review
2002
Drug Therapy of Urinary Urge Incontinence: A Systematic Review
Review
2000
Review
2000
Interstitial cystitis. Etiology, diagnosis, and treatment.
  • J. Nickel
  • Canadian family physician Medecin de famille…
  • 2000
  • Corpus ID: 16018712
OBJECTIVE To review current knowledge about the epidemiology, etiology, diagnosis, and treatment of interstitial cystitis, with… 
1997
1997
Effect of NS‐21, an Anticholinergic Drug with Calcium Antagonistic Activity, on Lower Urinary Tract Function in a Rat Model of Urinary Frequency
Background: NS‐21 is under development for the treatment of urinary frequency and urinary incontinence. The purpose of this study… 
1996
1996
Mechanisms of the Suppression of the Bladder Activity by Flavoxate
Background: This study was designed to clarify the primary site of action of flavoxate, clinically used for the treatment of… 
1993
1993
Double-blind crossover comparison of flavoxate and oxybutynin in women affected by urinary urge syndrome
This double-blind multiclinic crossover study was performed in order to compare the efficacy and tolerance of a 4-week treatment… 
1991
1991
Effects of different drugs on the cystometrogram in conscious rats.
Highly Cited
1990
Highly Cited
1990
Double-blind, placebo-controlled, cross-over study of flavoxate in the treatment of idiopathic detrusor instability.
Detrusor instability occurs in approximately 10% of the adult population, producing troublesome symptoms. The pharmacotherapy… 
Review
1989
Review
1989
Vesicoureteral reflux and voiding dysfunction: a prospective study.
1979
1979
Effect of flavoxate on hyperactive detrusor muscle.
The effect of Flavoxate on hyperactive detrusor contraction was studied in 37 patients, including 11 patients in whom the drug… 
1977
1977
Studies on the effect and mode of action of flavoxate in human urinary bladder and sphincter.
Flavoxate, a smooth muscle relaxant, compared with propantheline showed no significant difference in clinical effect on voiding… 
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