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Flavoxate

Known as: 2-Piperidinoethyl 3-methylflavone-8-carboxylate, 4H-1-Benzopyran-8-carboxylic acid, 3-methyl-4-oxo-2-phenyl-, 2-(1-piperidinyl)ethyl ester, 2-(1-Piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate 
A synthetic parasympatholytic with antimuscarinic, muscle relaxant and urinary antispasmodic properties. Flavoxate binds and inhibits muscarinic… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (6)

3-methylflavone-8-carboxylic acidFlavoxate HydrochlorideSpasuretUrispas
Esophageal AchalasiaGastric outlet obstructionGastrointestinal HemorrhageIn Blood

Broader (2)

ParasympatholyticsUrological Agents

Papers overview

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1985
1985
Mechanism of flavoxate antispasmodic activity comparative in vitro studies.
In order to clarify the pharmacological activity of flavoxate, its effect on the tone and spontaneous activity of the guinea-pig… 
1983
1983
A comparison between the combination emepronium bromide/flavoxate and emepronium bromide in the treatment of detrusor instability.
Emepronium bromide and flavoxate have both and separately been used with success in the treatment of detrusor instability. In… 
1980
1980
Motor urge incontinence: diagnosis and treatment.
A detailed study and analysis of several hundred cases of motor urge incontinence in the female is presented and summarized. This… 
1980
1980
Urodynamic response of unstable bladder to flavoxate.
Bladder instability provokes frequency, urgency, urge incontinence and enuresis in a great percentage of patients of both sexes… 
1977
1977
Studies on the effect and mode of action of flavoxate in human urinary bladder and sphincter.
Flavoxate, a smooth muscle relaxant, compared with propantheline showed no significant difference in clinical effect on voiding… 
1977
1977
Treatment of detrusor hyperreflexia in multiple sclerosis: a double-blind, crossover clinical trial comparing methantheline bromide (Banthine), flavoxate chloride (Urispas) and meladrazine tartrate…
34 patients suffering from detrusor hyperreflexia due to multiple sclerosis entered the trial and 32 patients accomplished. The… 
1975
1975
Flavoxate and 3-methylflavone-8-carboxylic acid. Assay methods in blood and urine, plasma-red cells repartition and stability.
The following assay methods for pharmacokinetic studies on flavoxate (F) and on its main metabolite, i.e. 3-methylflavone-8… 
1975
1975
Pharmacokinetics of flavoxate in rats.
The plasma levels, the urinary excretion and the biliary excretion of piperidinoethyl-3-methylflavone-8-carboxylate (flavoxate, F… 
1974
1974
The use of flavoxate in cystitis and renal colic.
SummaryTwo double-blind trials and one open study were carried out to assess the efficacy of the spasmolytic, flavoxate, in… 
1956
1956
[Results of pharmacological and clinical tests of a new synthetic parasympatholytic 9-(beta-piperidinoethyl) xanthenemethobromide (Spalisal Wander)].