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Flaviviral diseases

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses
Nucleoside analogs represent the largest class of small molecule-based antivirals, which currently form the backbone of… Expand
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2018
2018
A Reverse Genetics System for Zika Virus Based on a Simple Molecular Cloning Strategy
The Zika virus (ZIKV) has recently attracted major research interest as infection was unexpectedly associated with neurological… Expand
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Highly Cited
2017
Highly Cited
2017
Uncovering the Repertoire of Endogenous Flaviviral Elements in Aedes Mosquito Genomes
ABSTRACT Endogenous viral elements derived from nonretroviral RNA viruses have been described in various animal genomes. Whether… Expand
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Highly Cited
2016
Highly Cited
2016
Flavivirus NS1 protein in infected host sera enhances viral acquisition by mosquitoes
The arbovirus life cycle involves viral transfer between a vertebrate host and an arthropod vector, and acquisition of virus from… Expand
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2008
2008
Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase.
West Nile virus (WNV) is an emerging mosquito-borne flavivirus that causes neuronal damage in the absence of treatment. In many… Expand
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2007
2007
Yellow fever virus NS3 protease: peptide-inhibition studies.
A recombinant form of yellow fever virus (YFV) NS3 protease, linked via a nonapeptide to the minimal NS2B co-factor sequence… Expand
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Review
2006
Review
2006
Finding new medicines for flaviviral targets.
With the incidence of dengue fever increasing all over the world, there is an urgent need for therapies. While drug discovery for… Expand
Highly Cited
2005
Highly Cited
2005
Structural basis of West Nile virus neutralization by a therapeutic antibody
West Nile virus is a mosquito-borne flavivirus closely related to the human epidemic-causing dengue, yellow fever and Japanese… Expand
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Highly Cited
2002
Highly Cited
2002
Mechanism of De Novo Initiation by the Hepatitis C Virus RNA-Dependent RNA Polymerase: Role of Divalent Metals
ABSTRACT We functionally analyzed the role of metal ions in RNA-dependent RNA synthesis by three recombinant RNA-dependent RNA… Expand
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Highly Cited
1996
Highly Cited
1996
Characterization of the NTPase activity of Japanese encephalitis virus NS3 protein.
Japanese encephalitis (JE) virus NS3 protein and two N-terminally truncated (delta 1-148 and delta 1-323) forms of NS3 were… Expand
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