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First-Line Therapy

Known as: primary therapy, First Line Therapy, First Line Treatment 
Initial treatment used to reduce a cancer. First-line therapy is followed by other treatments, such as chemotherapy, radiation therapy, and hormone… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
18F-FDG PET Provides High-Impact and Powerful Prognostic Stratification in the Staging of Merkel Cell Carcinoma: A 15-Year Institutional Experience
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with limited evidence on the role of PET scanning. The primary… 
Highly Cited
2003
Highly Cited
2003
A cost–utility analysis of tension‐free vaginal tape versus colposuspension for primary urodynamic stress incontinence
Objective To assess the cost effectiveness of tension‐free vaginal tape compared with open Burch colposuspension as a primary… 
Highly Cited
2003
Highly Cited
2003
Moving disease biology from the lab to the clinic
Multiple myeloma (MM) cells home to and adhere to extracellular matrix proteins and to bone marrow stromal cells (BMSCs); and in… 
Review
2003
Review
2003
The multidisciplinary management of paragangliomas of the head and neck, Part 2.
Paragangliomas most commonly occur in the carotid body, jugulotympanic area, and vagus nerve but have also been reported in other… 
Highly Cited
1993
Highly Cited
1993
Treatment of late bone marrow relapse in children with acute lymphoblastic leukemia: a Pediatric Oncology Group study.
Children with acute lymphoblastic leukemia (ALL) who have completed 2.5 to 3 years of initial chemotherapy have an off-therapy… 
Highly Cited
1993
Highly Cited
1993
Restrictive Atrial Septal Communication as a Determinant of Outcome of Cardiac Transplantation for Hypoplastic Left Heart Syndrome
BackgroundInfant cardiac transplantation for hypoplastic left heart syndrome (HLHS) can be performed with a high success rate… 
Highly Cited
1989
Highly Cited
1989
Results of radiotherapy in recurrent endometrial carcinoma: a retrospective analysis of 51 patients.
Review
1986
Review
1986
Improved survival for soft tissue sarcoma of the extremities by regional hyperthermic perfusion, local excision and radiation therapy.
Soft tissue sarcomas continue to present problems with both local control of disease and death from distant metastases after… 
Highly Cited
1978
Highly Cited
1978
Bougienage is effective therapy for most benign esophageal strictures.
  • F. LanzaD. Graham
  • Journal of the American Medical Association (JAMA…
  • 1978
  • Corpus ID: 46158357
Esophageal stricture is the most frequent serious complication of reflux esophagitis. Bougienage was used as the primary therapy… 
Highly Cited
1976
Highly Cited
1976
Response and survival in advanced breast cancer after two non-cross-resistant combinations.
A prospective study with two cytotoxic combinations (cyclophosphamide, methotrexate, and fluorouracil (CMF), and adriamycin plus… 
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