Fenamates, antiinflammatory and antirheumatic drugs

Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase-1 (COX-1) and COX-2 enzymes. The NLRP3 inflammasome is a… Expand

BACKGROUND AND PURPOSE Fenamates are N-phenyl-substituted anthranilic acid derivatives clinically used as non-steroid anti… Expand

The non-steroidal anti-inflammatory drugs (NSAIDs) encompass a variety of structural classes, including salicylates, pyrazoles… Expand

The effect of fenamates on gap junctional intercellular communication was investigated in monolayers of normal rat kidney (NRK… Expand

The opening of potassium (K+) channels, causing hyperpolarization of the cell membrane, is a physiological means of decreasing… Expand

Genetic and physiological studies have established a link between potassium channel dysfunction and a number of neurological and… Expand

1. The perforated patch and conventional whole-cell recording techniques were used to study the action of flufenamic, mefenamic… Expand

N-Arylanthranilic acids, known generically as the fenamates, are nonsteroidal antiinflammatory drugs (NSAIDs) that block the… Expand

Dysmenorrhea, which may be primary or secondary, is the occurrence of painful uterine cramps during menstruation. Until a decade… Expand

The etiology of primary dysmenorrhea, which is the most common gynecologic complaint and cause of lost working hours, remains… Expand