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Fenamates, antiinflammatory and antirheumatic drugs

Known as: Fenamates 
National Institutes of Health

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Fenamates

Papers overview

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Highly Cited
2016
Highly Cited
2016
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase-1 (COX-1) and COX-2 enzymes. The NLRP3 inflammasome is a… 
Review
2009
Review
2009
Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: Animal and human studies
Review
2004
Review
2004
Enantioselective pharmacodynamics and pharmacokinetics of chiral non-steroidal anti-inflammatory drugs
  • A. Evans
  • European Journal of Clinical Pharmacology
  • 2004
  • Corpus ID: 21261283
The non-steroidal anti-inflammatory drugs (NSAIDs) encompass a variety of structural classes, including salicylates, pyrazoles… 
Highly Cited
2001
Highly Cited
2001
Fenamates: a novel class of reversible gap junction blockers.
The effect of fenamates on gap junctional intercellular communication was investigated in monolayers of normal rat kidney (NRK… 
Review
2000
Review
2000
Aspirin and other anti-inflammatory drugs
Salicylic acid, the active substance in plants used for thousands of years as medicaments, was synthesised by Kolbe in Germany in… 
Highly Cited
1999
Highly Cited
1999
Stilbenes and fenamates rescue the loss of IKS channel function induced by an LQT5 mutation and other IsK mutants
Genetic and physiological studies have established a link between potassium channel dysfunction and a number of neurological and… 
Highly Cited
1995
Highly Cited
1995
Comparison of the effects of fenamates on Ca‐activated chloride and potassium currents in rabbit portal vein smooth muscle cells
1 . The perforated patch and conventional whole‐cell recording techniques were used to study the action of flufenamic, mefenamic… 
Highly Cited
1993
Highly Cited
1993
1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.
N-Arylanthranilic acids, known generically as the fenamates, are nonsteroidal antiinflammatory drugs (NSAIDs) that block the… 
Review
1978
Review
1978
New concepts in dysmenorrhea.
Highly Cited
1968
Highly Cited
1968
Antagonism by Fenamates of Prostaglandin F2α and of Slow Reacting Substance on Human Bronchial Muscle
HISTAMINE, slow reacting substance in anaphylaxis (SRS-A) and prostaglandin F2α (PGF2α) are among substances obtained from lungs… 
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