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Factor VIIa

Known as: VIIa, Coagulation Factor, Coagulation factor VIIa, Factor VIIa [Chemical/Ingredient] 
Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
A beneficial effect of recombinant activated factor VII (rFVIIa) in Child‐Pugh class B and C patients with cirrhosis who have… Expand
Highly Cited
2007
Highly Cited
2007
Summary.  Background: Hemophilic patients with factor VIII (FVIII) and FIX inhibitors suffer from frequent bleeding episodes and… Expand
Review
2006
Review
2006
CONTEXT The US Food and Drug Administration (FDA) licensed recombinant human coagulation factor VIIa (rFVIIa) on March 25, 1999… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Uncontrolled bleeding is a leading cause of death in trauma. Two randomized, placebo-controlled, double-blind trials… Expand
Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Upper gastrointestinal bleeding (UGIB) is a severe and frequent complication of cirrhosis. Recombinant… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Recombinant coagulation factor VIIa (FVIIa) is approved for treating hemophiliacs with inhibitors. High-dose FVIIa has… Expand
Highly Cited
2000
Highly Cited
2000
Protease-activated receptor 2 (PAR2) is expressed by vascular endothelial cells and other cells in which its function and… Expand
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Highly Cited
1999
Highly Cited
1999
Surgical intervention failed to stop life-threatening bleeding caused by injury complicated by severe coagulopathy… Expand
Highly Cited
1997
Highly Cited
1997
High‐dose recombinant factor VIIa has been successfully used as therapy for haemophiliacs with inhibitors. The mechanism by which… Expand
Highly Cited
1996
Highly Cited
1996
Blood coagulation is initiated when tissue factor binds to coagulation factor Vila to give an enzymatically active complex which… Expand