Factor VIIa

Known as: VIIa, Coagulation Factor, Coagulation factor VIIa, Factor VIIa [Chemical/Ingredient] 
Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Tissue factor (TF) is a transmembrane receptor for Factor VII/VIIa (FVII/VIIa). It is constitutively expressed by cells… (More)
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Highly Cited
2006
Highly Cited
2006
Protease-activated receptors (PAR) are G protein-coupled receptors that function as cell-surface sensors for coagulant proteases… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Uncontrolled bleeding is a leading cause of death in trauma. Two randomized, placebo-controlled, double-blind trials… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Upper gastrointestinal bleeding (UGIB) is a severe and frequent complication of cirrhosis. Recombinant… (More)
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Review
2004
Review
2004
Recombinant factor VIIa was initially developed for the treatment of hemorrhagic episodes in hemophilic patients with inhibitors… (More)
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Highly Cited
2002
Highly Cited
2002
The ability of factor VIIa to initiate thrombin generation and clot formation in blood from healthy donors, blood from patients… (More)
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Highly Cited
2000
Highly Cited
2000
Protease-activated receptor 2 (PAR2) is expressed by vascular endothelial cells and other cells in which its function and… (More)
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Highly Cited
1999
Highly Cited
1999
Surgical intervention failed to stop life-threatening bleeding caused by injury complicated by severe coagulopathy… (More)
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Highly Cited
1997
Highly Cited
1997
High-dose recombinant factor VIIa has been successfully used as therapy for haemophiliacs with inhibitors. The mechanism by which… (More)
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Highly Cited
1996
Highly Cited
1996
Blood coagulation is initiated when tissue factor binds to coagulation factor Vila to give an enzymatically active complex which… (More)
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