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Factor VIIa Inhibitor PCI-27483

Known as: PCI-27483 
A reversible small-molecule inhibitor of activated factor VII (factor VIIa) with potential antineoplastic and antithrombotic activities. FVII, a… 
National Institutes of Health

Papers overview

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2011
2011
Phase I/II study of PCI-27483, a coagulation factor VIIa (FVIIa) inhibitor in patients with advanced pancreatic cancer receiving treatment with gemcitabine.
221 Background: PCI-27483 is a selective inhibitor of FVIIa, a serine protease activated by interaction with tissue factor (TF… 
2011
2011
Phase I/II pharmacokinetic and pharmacodynamic study of PCI-27483, a coagulation factor VIIa (FVIIa) inhibitor, in patients with advanced pancreatic cancer receiving treatment with gemcitabine.
e14610 Background: PCI-27483 is a selective inhibitor of FVIIa, a protease activated by interaction with tissue factor (TF). TF… 
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