Factor II deficiency

SummaryOral anticoagulants were introduced in the late 1940s and remain widely used today. Indications include prevention of… Expand

Antibiotics that contain a 1-N-methyl-5-thiotetrazole (MTT) side group have been associated with hypoprothrombinemia. In a… Expand

Several new antibiotics which contain an N-methyl-thio-tetrazole side chain have been associated with the development of… Expand

A dose-response curve for the hypoprothrombinemic effect of brodifacoum 3-[-3(4'-bromobiphenyl-4-yl) 1,2,3,4-tetrahydronaphth-1… Expand

Plasma vitamin K1 (phylloquinone) was assayed in normal adults and pregnant women at term and their babies by a method based on… Expand

Antipyrine has been used as a model drug to investigate the effects of liver disease on drug metabolism in man. A prolongation in… Expand

The development of vitamin K deficiency, vitamin K requirement and warfarin susceptibility were studied in several types of… Expand

SUMMARY. The family pedigrees of three patients with congenital ‘true’hypoprothrombinaemia are reported. By means of a specific… Expand

Abstract During therapy with chloral hydrate one of its major metabolites, trichloroacetic acid, accumulates in plasma to more… Expand