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Factor II deficiency

Known as: HYPOPROTHROMBINEMIA, Deficiency, factor II, Deficiency, prothrombin 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Blood Coagulation Disorders
Flood Factor Deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1988
Review
1988
Antibiotic-associated hypoprothrombinaemia.
  • J. Lipsky
  • The Journal of antimicrobial chemotherapy
  • 1988
  • Corpus ID: 43173834
Hypoprothrombinaemia is regarded as a serious adverse effect of antimicrobial therapy. This effect has commonly been attributed… 
Highly Cited
1984
Highly Cited
1984
Mechanism of the inhibition of the gamma-carboxylation of glutamic acid by N-methylthiotetrazole-containing antibiotics.
  • J. Lipsky
  • Proceedings of the National Academy of Sciences…
  • 1984
  • Corpus ID: 21139894
Antibiotics that contain a 1-N-methyl-5-thiotetrazole (MTT) side group have been associated with hypoprothrombinemia. In a… 
Highly Cited
1983
Highly Cited
1983
N-METHYL-THIO-TETRAZOLE INHIBITION OF THE GAMMA CARBOXYLATION OF GLUTAMIC ACID: POSSIBLE MECHANISM FOR ANTIBIOTIC-ASSOCIATED HYPOPROTHROMBINAEMIA
Several new antibiotics which contain an N-methyl-thio-tetrazole side chain have been associated with the development of… 
Highly Cited
1983
Highly Cited
1983
Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats.
A dose-response curve for the hypoprothrombinemic effect of brodifacoum 3-[-3(4'-bromobiphenyl-4-yl) 1,2,3,4-tetrahydronaphth-1… 
Highly Cited
1982
Highly Cited
1982
PLASMA VITAMIN K1 IN MOTHERS AND THEIR NEWBORN BABIES
Plasma vitamin K1 (phylloquinone) was assayed in normal adults and pregnant women at term and their babies by a method based on… 
Highly Cited
1973
Highly Cited
1973
Determinants of serum antipyrine half-lives in patients with liver disease
Antipyrine has been used as a model drug to investigate the effects of liver disease on drug metabolism in man. A prolongation in… 
1973
1973
Warfarin resistance and vitamin K requirement in the rat
The development of vitamin K deficiency, vitamin K requirement and warfarin susceptibility were studied in several types of… 
Highly Cited
1971
Highly Cited
1971
The Hereditary Transmission of Congenital ‘True’Hypoprothrombinaemia
  • A. Girolami
  • British journal of haematology
  • 1971
  • Corpus ID: 32175551
SUMMARY. The family pedigrees of three patients with congenital ‘true’hypoprothrombinaemia are reported. By means of a specific… 
Highly Cited
1970
Highly Cited
1970
Potentiation of warfarin-induced hypoprothrombinemia by chloral hydrate.
Abstract During therapy with chloral hydrate one of its major metabolites, trichloroacetic acid, accumulates in plasma to more… 
Highly Cited
1943
Highly Cited
1943
STUDIES ON THE HEMORRHAGIC SWEET CLOVER DISEASE XI. HYPOPROTHROMBINEMIA IN THE RAT INDUCED BY SALICYLIC ACID
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