Factor II deficiency

Oral anticoagulants were introduced in the late 1940s and remain widely used today. Indications include prevention of thrombosis… (More)

Human leptospirosis of the classical and severe icterohemorrhagic type, usually due to the L. icterohaemorrhagiae serogroup, is… (More)

Antibiotics that contain a 1-N-methyl-5-thiotetrazole (MTT) side group have been associated with hypoprothrombinemia. In a… (More)

A dose-response curve for the hypoprothrombinemic effect of brodifacoum 3-[-3(4'-bromobiphenyl-4-yl) 1,2,3,4-tetrahydronaphth-1… (More)

Several new antibiotics which contain an N-methyl-thio-tetrazole side chain have been associated with the development of… (More)

Plasma vitamin K1 (phylloquinone) was assayed in normal adults and pregnant women at term and their babies by a method based on… (More)

Necrosis of the skin is a rare complication of oral anticoagulation therapy by coumarin congeners. Three males receiving… (More)

Antipyrine has been used as a model drug to investigate the effects of liver disease on drug metabolism in man. A prolongation in… (More)