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FXI-ASO

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Genetically Determined FXI (Factor XI) Levels and Risk of Stroke
Background and Purpose— FXI (factor XI) is involved in thrombus propagation and stabilization. It is unknown whether lower FXI… Expand
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2016
2016
In vitro comparison of the effect of two factor XI (FXI) concentrates on thrombin generation in major FXI deficiency
Bleeding risk in factor XI (FXI) deficiency following surgery may be reduced by treatment with either of two FXI concentrates… Expand
Highly Cited
2015
Highly Cited
2015
Factor XI antisense oligonucleotide for prevention of venous thrombosis.
BACKGROUND Experimental data indicate that reducing factor XI levels attenuates thrombosis without causing bleeding, but the role… Expand
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2015
2015
Factor XI‐related thrombosis and the role of concentrate treatment in factor XI deficiency
The management of inherited factor XI (FXI) deficiency poses problems because of the poor relationship between the measured FXI… Expand
2015
2015
Anticoagulation therapy: Reducing factor XI with antisense oligonucleotides superior to endoxaparin for postoperative venous thromboembolism
  • J. Duarte
  • Nature Reviews Cardiology
  • 2015
    • Corpus ID: 27131775
Anticoagulation therapy: Reducing factor XI with antisense oligonucleotides superior to endoxaparin for postoperative venous… Expand
Highly Cited
2014
Highly Cited
2014
Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis
BACKGROUND: Patients undergoing total knee arthroplasty are at risk for postoperative venous thromboembolism (VTE). The… Expand
2014
2014
Co-Dependence of Extreme Events in High Frequency FX Returns
In this paper, we investigate extreme events in high frequency, multivariate FX returns within a purposely built framework. We… Expand
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Highly Cited
2004
Highly Cited
2004
Dominant factor XI deficiency caused by mutations in the factor XI catalytic domain.
The bleeding diathesis associated with hereditary factor XI (fXI) deficiency is prevalent in Ashkenazi Jews, in whom the disorder… Expand
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2004
2004
Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI–Glu555): a cross‐reactive material positive variant defective in factor IX activation
Summary.  During normal hemostasis, the coagulation protease factor (F)XIa activates FIX. Hereditary deficiency of the FXIa… Expand
2000
2000
Reliability-Based Design Sensitivity Analysis and Optimization for the Hyper-Elastic Structure Using the Meshfree Method
In this paper, efficient design sensitivity analysis (DSA) and optimization methods are presented to support reliability-based… Expand
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