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Background and Purpose— FXI (factor XI) is involved in thrombus propagation and stabilization. It is unknown whether lower FXI… Expand Bleeding risk in factor XI (FXI) deficiency following surgery may be reduced by treatment with either of two FXI concentrates… Expand BACKGROUND
Experimental data indicate that reducing factor XI levels attenuates thrombosis without causing bleeding, but the role… Expand The management of inherited factor XI (FXI) deficiency poses problems because of the poor relationship between the measured FXI… Expand Anticoagulation therapy: Reducing factor XI with antisense oligonucleotides superior to endoxaparin for postoperative venous… Expand BACKGROUND: Patients undergoing total knee arthroplasty are at risk for postoperative venous thromboembolism (VTE). The… Expand In this paper, we investigate extreme events in high frequency, multivariate FX returns within a purposely built framework. We… Expand The bleeding diathesis associated with hereditary factor XI (fXI) deficiency is prevalent in Ashkenazi Jews, in whom the disorder… Expand Summary. During normal hemostasis, the coagulation protease factor (F)XIa activates FIX. Hereditary deficiency of the FXIa… Expand In this paper, efficient design sensitivity analysis (DSA) and optimization methods are presented to support reliability-based… Expand