FXI-ASO

Essentials Reduction of three disulfide bonds in factor (F) XI enhances chromogenic substrate cleavage. We measured FXI activity… (More)

Antithrombotic therapies are often associated with an increased risk of bleeding, but factor XI has been identified as a… (More)

INTRODUCTION Menstrual bleeding, pregnancy and delivery present an intrinsic haemostatic challenge to women with bleeding… (More)

The management of inherited factor XI (FXI) deficiency poses problems because of the poor relationship between the measured FXI… (More)

Even though nearly 20 years have passed since thrombin-mediated factor (f)XI activation was first described,1,2 the relevance of… (More)

BACKGROUND AND OBJECTIVES Factor XI (FXI) deficiency is a rare autosomal recessive disorder, the main manifestation of which is… (More)

We have studied two heterozygous unrelated CRM- non-Jewish FXI-deficient patients. Neither of the patients carries a previously… (More)