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FR 901533

Known as: FR901533 
National Institutes of Health

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WS 79089B

Papers overview

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2002
2002
Chronic effects of an endothelin-converting enzyme inhibitor on cardiorenal and hormonal function in heart failure.
Endothelin (ET)-converting enzyme (ECE) is a rate-limiting step in ET-1 generation, and its expression and activity are increased… 
2001
2001
Protective role of an endothelin-converting enzyme inhibitor (FR901533) in hepatic ischemia/reperfusion injury.
INTRODUCTION There is evidence that endothelin (ET) contributes to disturbances of the hepatic microcirculation after warm… 
2000
2000
Selective upregulation of endothelin converting enzyme-1a in the human failing heart.
BACKGROUND Increased plasma levels of endothelin-1 (ET-1) occur with congestive heart failure (CHF), but the components of the… 
1999
1999
The role of endothelin-converting enzyme-1 in the development of alpha1-adrenergic-stimulated hypertrophy in cultured neonatal rat cardiac myocytes.
BACKGROUND Accumulating evidence suggests that the local synthesis of endothelin-1 (ET-1) plays a role in the development of… 
1998
1998
Endothelin converting enzyme inhibitor protects development of right ventricular overload and medial thickening of pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension.
1995
1995
Biological and pharmacological properties of highly selective new endothelin converting enzyme inhibitor WS79089B isolated from Streptosporangium roseum No. 79089.
WS79089B a highly specific endothelin converting enzyme (ECE) inhibitor has been isolated from the fermentation broth of… 
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