FR 900098

Known as: FR-900098 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2015
012319802015

Papers overview

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2016
2016
FR-900098 is an inhibitor of 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase, the second enzyme in the non-mevalonate… (More)
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2015
2015
We report here the enzymatic biosynthesis of FR-900098 analogues and establish an in vivo platform for the biosynthesis of an N… (More)
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2012
2012
A number of pathogens, including the causative agents of tuberculosis and malaria, synthesize the essential isoprenoid precursor… (More)
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2012
2012
Fosfomycin is a wide-spectrum antibiotic that is used clinically to treat acute cystitis in the United States. The compound is… (More)
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2010
2010
FR-900098 is a potent chemotherapeutic agent for the treatment of malaria. Here we report the heterologous production of this… (More)
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2010
2010
Fosmidomycin and its analogue FR-900098 are potent inhibitors of 1-deoxy-d-xylulose 5-phosphate reducto-isomerase (DXR), the… (More)
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2000
2000
Two Pseudomonas aeruginosa genes encoding the enzymes 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase… (More)
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Highly Cited
1999
Highly Cited
1999
A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium falciparum was shown to represent an effective… (More)
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1980
1980
A strain of Streptomyces, isolated from a soil sample and identified as Streptomyces rubellomurinus sp. nov., has been found to… (More)
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1980
1980
Three phosphonic acid antibiotics were found to be produced in the fermentation broths of Streptomyces. FR-31564 and FR-32863… (More)
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