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FR 118487

Known as: FR-118487 
National Institutes of Health

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Spiro Compounds

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2010
2010
Anti-angiogenic therapy on hepatocellular carcinoma development and progression.
2001
2001
Prevention of Hepatic and Peritoneal Metastases by the Angiogenesis Inhibitor FR‐118487 after Removal of Growing Tumor in Mice
We established a mouse “primary tumor resection model” in which a transplanted tumor was resected after an orthotopic… 
1999
1999
Inhibitory Effect of the Angiogenesis Inhibitor FR-118487 on Liver Metastasis in a Rabbit Colon Cancer Model by Continuous Intraarterial Infusion.
VX2腫瘍を用いた家兎大腸癌モデルで, 血管新生阻害剤FR-118487 (FR) の持続肝動脈内投与の肝転移再発抑制効果について検討した. 大腸癌原発巣を切除後, A群:プロピレングリコール (PG) 持続肝動注群, B群: FR持続肝動注群, C… 
1998
1998
The suppression of postoperative liver metastasis caused by the continuous intraportal infusion of angiogenesis inhibitor FR-118487 in a rabbit colon cancer model
The inhibitory effect of FR-118487, a potent angiogenesis inhibitor, on neovascularization induced by the VX2 tumor was confirmed… 
1998
1998
The Suppression of Postoperative Liver Metastasis Caused by the Continuous Intraportal Infusion of Angiogenesis Inhibitor FR-118487 in a Rabbit Colon Cancer Model(家兎大腸癌モデルにおける血管新生阻害剤FR-118487…
1998
1998
The Suppression of Postoperative Liver Metastasis Caused by the Continuous Intraportal Infusion of Angiogenesis Inhibitor FR-118487 in a Rabbit Colon Cancer Model
1996
1996
II-242 血管新生抑制剤 (FR-118487) によるラット実験肝癌に対する効果 : 臨床応用へむけて( 第48回日本消化器外科学会総会)
1995
1995
[Suppression of postoperative liver metastases from colon cancer by continuous intraportal infusion of an angiogenesis inhibitor FR-118487].
A rabbit VX2 colon cancer model with spontaneous liver metastases was used to evaluate the antitumor effect of an angiogenesis… 
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