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FN1 protein, human

Known as: CIG, Large, External, Transformation-Sensitive Protein, Large External Transformation-Sensitive Protein 
Fibronectin (2386 aa, ~263 kDa) is encoded by the human FN1 gene. This protein is involved in cell adhesion- and migration-dependent processes… 
National Institutes of Health

Related topics

Related topics

29 relations
Blood coagulationCell AdhesionCell Adhesion MoleculesCell Movement

Broader (1)

Fibronectins

Papers overview

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Highly Cited
1981
Highly Cited
1981
Receptors for cold-insoluble globulin (plasma fibronectin) on human monocytes
This investigation focused on the role played by cold-insoluble globulin (CIg, plasma fibronectin) in monocyte function. Surface… 
Highly Cited
1979
Highly Cited
1979
Initial adhesion of human fibroblasts in serum-free medium: Possible role of secreted fibronectin
Highly Cited
1979
Highly Cited
1979
Fibronectin and proteoglycans as determinants of cell-substratum adhesion.
When normal or SV40-transformed Balb/c 3T3 cells are treated with the Ca++-specific chelator EGTA, they round up and pull away… 
Highly Cited
1977
Highly Cited
1977
Interactions Among Heparin, Cold-Insoluble Globulin, and Fibrinogen in Formation of the Heparin Precipitable Fraction of Plasma
Fibrinogen and the cold-insoluble globulin of plasma (CIg) are the main protein components of the heparin cryoprecipi table… 
Highly Cited
1977
Highly Cited
1977
Markers of neoplastic transformation in epithelial cell lines derived from human carcinomas.
Density-dependent inhibition of growth, plating efficiency on confluent monolayers of 3T3 cells, and growth in agar have been… 
Highly Cited
1977
Highly Cited
1977
Cold-insoluble globulin mediates the adhesion of rat liver cells to plastic Petri dishes.
Highly Cited
1976
Highly Cited
1976
Plasma membrane glycoprotein which mediates adhesion of fibroblasts to collagen
DEFECTS in cell behaviour associated with malignancy may be causally related to alterations in the plasma membrane of the cell on… 
Highly Cited
1975
Highly Cited
1975
Interaction of soluble fibroblast surface antigen with fribrinogen and fibrin
A cell-type specific glycoprotein antigen (SFA) from fibroblast surface appears in human plasma and serum. The amount of SFA in… 
Highly Cited
1975
Highly Cited
1975
The cold-insoluble globulin of human plasma: studies of its essential structural features.
Highly Cited
1970
Highly Cited
1970
The cold-insoluble globulin of human plasma. I. Purification, primary characterization, and relationship to fibrinogen and other cold-insoluble fraction components.
Abstract The cold-insoluble globulin (CI-globulin) of human plasma has been highly purified. Starting with Fraction I-1, or… 
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