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FMN2 gene

Known as: FMN2, FORMIN 2 
 
National Institutes of Health

Papers overview

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2019
2019
A Novel circFMN2 Promotes Tumor Proliferation in CRC by Regulating the miR-1182/hTERT Signaling Pathways.
BACKGROUND Circular RNAs (circRNAs) are a class of non-coding RNAs broadly expressed in cells of various species. However, the… Expand
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Highly Cited
2018
Highly Cited
2018
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division
Mitochondrial division requires division of both the inner and outer mitochondrial membranes (IMM and OMM, respectively… Expand
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Highly Cited
2017
Highly Cited
2017
Genome wide mapping of long range contacts unveils DNA Double Strand Breaks clustering at damaged active genes
The ability of DNA double-strand breaks (DSBs) to cluster in mammalian cells has been a subject of intense debate in recent years… Expand
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2016
2016
RETRACTED: FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis
Cell migration in confined 3D tissue microenvironments is critical for both normal physiological functions and dissemination of… Expand
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2016
2016
Formin 2 regulates the stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo
Growth cone filopodia are actin-based mechanosensory structures that are essential for chemoreception and the generation of… Expand
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Highly Cited
2014
Highly Cited
2014
Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism
An in vitro study reveals how the three actin binding proteins profilin, formin 2, and Spire functionally cooperate by a ping… Expand
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2014
2014
Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability.
Dendritic spines represent the major site of neuronal activity in the brain; they serve as the receiving point for… Expand
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2013
2013
De novo deletion of FMN2 in a girl with mild non-syndromic intellectual disability.
We present the case of a child with mild non-syndromic intellectual disability in whom array genomic hybridization revealed a de… Expand
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Highly Cited
2011
Highly Cited
2011
Symmetry breaking in mouse oocytes requires transient F-actin meshwork destabilization
Female meiotic divisions are extremely asymmetric, giving rise to a large oocyte and small degenerating polar bodies, keeping the… Expand
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2011
2011
Gene profiling of Graffi murine leukemia virus-induced lymphoid leukemias: identification of leukemia markers and Fmn2 as a potential oncogene.
The Graffi murine leukemia virus induces a large spectrum of leukemias in mice and thus provides a good model to compare the… Expand
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