FMN2 gene

Known as: FMN2, FORMIN 2 
 
National Institutes of Health

Papers overview

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2018
2018
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division
Mitochondrial division requires division of both the inner and outer mitochondrial membranes (IMM and OMM, respectively… (More)
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2017
2017
Genome wide mapping of long range contacts unveils DNA Double Strand Breaks clustering at damaged active genes
The ability of DNA double-strand breaks (DSBs) to cluster in mammalian cells has been a subject of intense debate in recent years… (More)
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2016
2016
Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments.
Formin 2 (Fmn2), a member of the FMN family of formins, plays an important role in early development. This formin cooperates with… (More)
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2014
2014
Spire and Formin 2 Synergize and Antagonize in Regulating Actin Assembly in Meiosis by a Ping-Pong Mechanism
In mammalian oocytes, three actin binding proteins, Formin 2 (Fmn2), Spire, and profilin, synergistically organize a dynamic… (More)
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2014
2014
Biallelic truncating mutations in FMN2, encoding the actin-regulatory protein Formin 2, cause nonsyndromic autosomal-recessive intellectual disability.
Dendritic spines represent the major site of neuronal activity in the brain; they serve as the receiving point for… (More)
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2013
2013
De novo deletion of FMN2 in a girl with mild non-syndromic intellectual disability.
We present the case of a child with mild non-syndromic intellectual disability in whom array genomic hybridization revealed a de… (More)
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2013
2013
FMN2 is a novel regulator of the cyclin-dependent kinase inhibitor p21
We have identified the human FMN2 gene as a novel target regulated by induction of p14ARF and by multiple other stress responses… (More)
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2013
2013
Metastasis Suppressor microRNA-335 Targets the Formin Family of Actin Nucleators
MiRNAs can have pleiotropic effects by targeting multiple genes belonging to diverse signalling networks. Alternatively, miRNAs… (More)
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2011
2011
Gene profiling of Graffi murine leukemia virus-induced lymphoid leukemias: identification of leukemia markers and Fmn2 as a potential oncogene.
The Graffi murine leukemia virus induces a large spectrum of leukemias in mice and thus provides a good model to compare the… (More)
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2011
2011
Symmetry breaking in mouse oocytes requires transient F-actin meshwork destabilization.
Female meiotic divisions are extremely asymmetric, giving rise to a large oocyte and small degenerating polar bodies, keeping the… (More)
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