FK 448

Known as: FK-448

National Institutes of Health

Papers overview

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2006

2006

proteínas : III . Aplicação à insulina

Oral delivery systems for peptides and proteins: III. Application to insulin Insulin is an important therapeutic protein… (More)

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Review

1998

Review

1998

The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins.

Andreas Bernkop-Schnürch
Journal of controlled release : official journal…
1998

The peroral administration of peptide drugs is a major challenge to pharmaceutical science. In order to provide a sufficient… (More)

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1988

1988

[Promoting effect of the chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats].

Noriko Yokoo, Setsuro Ebiya-Cho Fujii, Takuya Suzuki
Yakugaku zasshi : Journal of the Pharmaceutical…
1988

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1985

1985

Promoting effect of the new chymotrypsin inhibitor FK-448 on the intestinal absorption of insulin in rats and dogs.

Shinobu Fujii, Tōru Yokoyama, K. Ikegaya, Fuminori Sato, Noriko Yokoo
The Journal of pharmacy and pharmacology
1985

FK-448 is a potent and specific inhibitor of chymotrypsin, which enhances the intestinal absorption of insulin in rats and dogs… (More)

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1985

1985

EFFECT OF NEW CHYMOTRYPSIN INHIBITOR (FK-448) ON INTESTINAL ABSORPTION OF INSULIN

Masaki Shinomiya, Kohji Shirai, Yasushi Saito, Shigemasa Yoshida, Nobuya Matsuoka
The Lancet
1985

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1984

1984

New synthetic inhibitors of chymotrypsin.

Shinobu Fujii, Tōru Yokoyama, K. Ikegaya, Noriko Yokoo
Journal of biochemistry
1984

4-Substituted carbonylphenyl ester derivatives were prepared and their inhibitory effects on chymotrypsin, trypsin, thrombin… (More)

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