FGF21 gene

Known as: FGF21, FIBROBLAST GROWTH FACTOR 21, Fibroblast Growth Factor 21 Gene 
This gene plays a role in signal transduction.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Fibroblast growth factors (FGFs) 15/19 and 21 belong to a subfamily of FGFs that function as hormones. Produced in response to… (More)
  • table 1
  • figure 1
Is this relevant?
2013
2013
Dietary intake of macronutrients (carbohydrate, protein, and fat) has been associated with risk of chronic conditions such as… (More)
  • figure 1
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Certain white adipose tissue (WAT) depots are readily able to convert to a "brown-like" state with prolonged cold exposure or… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2012
Highly Cited
2012
FGF21 is a multifunctional metabolic regulator. The co-factor βKlotho (KLB) allows FGF21 to signal via FGF receptors. Given the… (More)
Is this relevant?
Highly Cited
2012
Highly Cited
2012
BACKGROUND Recent studies suggest that betaKlotho (KLB) and endocrine FGF19 and FGF21 redirect FGFR signaling to regulation of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Fibroblast growth factor-21 (FGF21) signaling requires the presence of beta-Klotho, a co-receptor with a very short cytoplasmic… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Fibroblast growth factor-21 (FGF21) functions as a metabolic regulator. The FGF21 transcript is reported to be abundantly… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
FGF21 is a critical metabolic regulator, pivotal for fasting adaptation and directly regulated by PPARalpha in rodents. However… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Peroxisome proliferator-activated receptor alpha (PPARalpha) regulates the utilization of fat as an energy source during… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Mice fed a high-fat, low-carbohydrate ketogenic diet (KD) exhibit marked changes in hepatic metabolism and energy homeostasis… (More)
Is this relevant?