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FGD5 gene

Known as: FYVE, RhoGEF and PH domain containing 5, FYVE, RhoGEF and PH Domain Containing 5 Gene, FLJ39957 
This gene plays a role in the reorganization of the actin cytoskeleton.
National Institutes of Health

Related topics

Related topics

4 relations
Cytoskeletal ModelingFGD6 geneRegulation of Cell ShapeSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Faculty Opinions recommendation of VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
  • J. V. van Buul
  • Faculty Opinions – Post-Publication Peer Review…
  • 2019
  • Corpus ID: 209732511
2019
2019
Faculty Opinions recommendation of VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
  • A. Kazlauskas
  • Faculty Opinions – Post-Publication Peer Review…
  • 2019
  • Corpus ID: 202994404
2018
2018
Abstract 1007: Durvalumab + tremelimumab increase T cells and decrease expression of genes involved in angiogenesis, EMT, and the Th2 pathway in the NSCLC tumor microenvironment
Background Cancer cells utilize multiple mechanisms to suppress the development of an effective anti-tumor immune response… 
2017
2017
FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling
Objective— VEGF (vascular endothelial growth factor-A) signaling to the endothelial cell (EC) through VEGFR2 (VEGF receptor-2) is… 
2017
2017
FGD5 (Faciogenital Dysplasia-5) Regulates VEGF (Vascular Endothelial Growth Factor-A) Receptor-2 Coupling to PI3 (Phosphoinositide-3) Kinase and Receptor Recycling
Objective— VEGF (vascular endothelial growth factor-A) signaling to the endothelial cell (EC) through VEGFR2 (VEGF receptor-2) is… 
2014
2014
Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells
BACKGROUNDA function for the microRNA (miRNA) pathway in vascular development and angiogenesis has been firmly established… 
2013
2013
FGD5 promotes VEGF-A signaling via inhibition of VEGF-receptor ubiquitination and degradation
Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly… 
2012
2012
FGD5 deficiency confers defective matrix adhesion and survival among endothelial cells
FGD5 is a putative Rho family guanine nucleotide exchange factor enriched in vascular endothelial cells (EC). We observed FGD5… 
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