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FDPS wt Allele

Known as: FPPS, Farnesyl Diphosphate Synthase wt Allele, Farnesyl Pyrophosphate Synthetase, Dimethylallyltranstransferase, Geranyltranstransferase Gene 
Human FDPS wild-type allele is located in the vicinity of 1q22 and is approximately 12 kb in length. This allele, which encodes farnesyl… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
The ability of bisphosphonates ((HO)(2)P(O)CR(1)R(2)P(O)(OH)(2)) to inhibit bone resorption has been known since the 1960s, but… Expand
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Highly Cited
2008
Highly Cited
2008
The nitrogen-containing bisphosphonates (N-BPs) are the main drugs currently used to treat diseases characterized by excessive… Expand
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Review
2007
Review
2007
SummaryBisphosphonates (BPs) are well established as the leading drugs for the treatment of osteoporosis. There is new knowledge… Expand
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Highly Cited
2007
Highly Cited
2007
Interferons initiate the host antiviral response by inducing a number of genes, most with no defined antiviral function. Here we… Expand
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Review
2007
Review
2007
The bisphosphonates (BPs) are well established as the treatments of choice for disorders of excessive bone resorption, including… Expand
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Highly Cited
2006
Highly Cited
2006
Osteoporosis and low bone mass are currently estimated to be a major public health risk affecting >50% of the female population… Expand
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Review
2006
Review
2006
  • R. Russell
  • Annals of the New York Academy of Sciences
  • 2006
  • Corpus ID: 20706956
The discovery and development of the bisphosphonates (BPs) as a major class of drugs for the treatment of bone diseases has been… Expand
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Highly Cited
2006
Highly Cited
2006
To understand the structural basis for bisphosphonate therapy of bone diseases, we solved the crystal structures of human… Expand
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Highly Cited
2004
Highly Cited
2004
Farnesyl pyrophosphate synthetase (FPPS) synthesizes farnesyl pyrophosphate through successive condensations of isopentyl… Expand
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Highly Cited
2003
Highly Cited
2003
Bisphosphonates (BPS) inhibit bone resorption and are divided into two classes according to their chemical structure and… Expand
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