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FD 895

Known as: FD-895 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Macrolides

Papers overview

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2014
2014
Asymmetric synthesis of C11-C23 fragment of Pladienolide B
Synthesis of C11-C23 fragment of an antitumor natural product, Pladienolide B, in gram-scale, is described. The key steps… 
2013
2013
Stabilized cyclopropane analogs of the splicing inhibitor FD-895.
Targeting the spliceosome with small molecule inhibitors provides a new avenue to target cancer by intercepting alternate… 
2012
2012
Fd-895 and Pladienolide B Inhibit mRNA Splicing and Induce Apoptosis in Chronic Lymphocytic Leukemia
Abstract 3890 Alternative splicing plays a fundamental role in human biology and its relevance in cancer is rapidly emerging… 
2007
2007
A synthetic entry to pladienolide B and FD-895.
1994
1994
Isolation and characterization of a new 12-membered macrolide FD-895.
During the course of our screening program for natural product drugs effective against multidrug resistant cells by using… 
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