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FAM83B gene

Known as: FAM83B, FLJ30642, family with sequence similarity 83 member B 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Knocking down FAM83B inhibits endometrial cancer cell proliferation and metastasis by silencing the PI3K/AKT/mTOR pathway.
Family with sequence similarity 83 member B (FAM83B) has been recently identified as an oncogene involved in the development of… Expand
2019
2019
FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC
Although targeted therapy has improved the survival rates in the last decade, non-small-cell lung cancer (NSCLC) is still the… Expand
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2019
2019
Systematic Analysis of Gene Expression in Lung Adenocarcinoma and Squamous Cell Carcinoma with a Case Study of FAM83A and FAM83B
Introduction: In our previous study, we constructed a Lung Cancer Explorer (LCE) database housing lung cancer-specific expression… Expand
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2018
2018
Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expression
Substantial evidence shows that long non-coding RNAs (lncRNAs) participate in many biological mechanisms, and their dysregulation… Expand
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2018
2018
Differential genomics and transcriptomics between tyrosine kinase inhibitor-sensitive and -resistant BCR-ABL-dependent chronic myeloid leukemia
Previously, it has been stated that the BCR-ABL fusion-protein is sufficient to induce Chronic Myeloid Leukemia (CML), but… Expand
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2017
2017
High Expression of FAM83B Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma and Correlates with Cell Cycle and Cell Proliferation
FAM83B (family with sequence similarity 83, member B) seems to emerge as a new class of players involved in the development of a… Expand
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2014
2014
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B
Despite the progress made in targeted anticancer therapies in recent years, challenges remain. The identification of new… Expand
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2013
2013
FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies
Therapies targeting MAPK and AKT/mTOR signaling are currently being evaluated in clinical trials for several tumor types. However… Expand
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Highly Cited
2012
Highly Cited
2012
Triple SILAC to Determine Stimulus Specific Interactions in the Wnt Pathway
Many important regulatory functions are performed by dynamic multiprotein complexes that adapt their composition and activity in… Expand
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2012
2012
FAM83A and FAM83B: candidate oncogenes and TKI resistance mediators.
  • S. Grant
  • The Journal of clinical investigation
  • 2012
    • Corpus ID: 28367882
The growth and survival of tumor cells can depend upon the expression of a single oncogene, and therapeutically targeting this… Expand
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