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FAM83B gene

Known as: FAM83B, FLJ30642, family with sequence similarity 83 member B 
National Institutes of Health

Papers overview

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2020
2020
Analysis of gene expression profiles of lung cancer subtypes with machine learning algorithms.
2019
2019
FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC
Although targeted therapy has improved the survival rates in the last decade, non-small-cell lung cancer (NSCLC) is still the… 
2019
2019
Knocking down FAM83B inhibits endometrial cancer cell proliferation and metastasis by silencing the PI3K/AKT/mTOR pathway.
Highly Cited
2018
Highly Cited
2018
Long intergenic non-coding RNA 00324 promotes gastric cancer cell proliferation via binding with HuR and stabilizing FAM83B expression
Substantial evidence shows that long non-coding RNAs (lncRNAs) participate in many biological mechanisms, and their dysregulation… 
2017
2017
High Expression of FAM83B Predicts Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma and Correlates with Cell Cycle and Cell Proliferation
FAM83B (family with sequence similarity 83, member B) seems to emerge as a new class of players involved in the development of a… 
Review
2014
Review
2014
Conserved Oncogenic Behavior of the FAM83 Family Regulates MAPK Signaling in Human Cancer
FAM83B (family with sequence similarity 83, member B) was recently identified as a novel oncogene involved in activating CRAF… 
2014
2014
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83B
Despite the progress made in targeted anticancer therapies in recent years, challenges remain. The identification of new… 
Highly Cited
2013
Highly Cited
2013
FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies
Therapies targeting MAPK and AKT/mTOR signaling are currently being evaluated in clinical trials for several tumor types. However… 
2012
2012
FAM83A and FAM83B: candidate oncogenes and TKI resistance mediators.
  • S. Grant
  • Journal of Clinical Investigation
  • 2012
  • Corpus ID: 28367882
The growth and survival of tumor cells can depend upon the expression of a single oncogene, and therapeutically targeting this… 
Highly Cited
2011
Highly Cited
2011
Triple SILAC to Determine Stimulus Specific Interactions in the Wnt Pathway
Many important regulatory functions are performed by dynamic multiprotein complexes that adapt their composition and activity in… 
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