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FAM3C gene

Known as: FAM3C, family with sequence similarity 3 member C, ILEI 
This gene is involved in the induction of epithelial-mesenchymal transition.
National Institutes of Health

Related topics

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3 relations
FAM3A geneFAM3C protein, humanepithelial to mesenchymal transition

Papers overview

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2019
2019
FAM3C‐YY1 axis is essential for TGFβ‐promoted proliferation and migration of human breast cancer MDA‐MB‐231 cells via the activation of HSF1
Family with sequence similarity three member C (FAM3C) (interleukin‐like EMT inducer [ILEI]), heat shock factor 1 (HSF1) and Ying… 
2014
2014
ILEI drives epithelial to mesenchymal transition and metastatic progression in the lung cancer cell line A549
Transforming growth factor beta (TGF-β) induces epithelial–mesenchymal transition (EMT) accompanied by cellular differentiation… 
2014
2014
The FAM3 superfamily member ILEI ameliorates Alzheimer’s disease-like pathology by destabilizing the penultimate amyloid-β precursor
Accumulation of amyloid-β peptide (Aβ) in the brain underlies the pathogenesis of Alzheimer’s disease (AD). Aβ is produced by… 
2014
2014
ILEI: a novel marker for epithelial–mesenchymal transition and poor prognosis in colorectal cancer
Accumulating evidence over the past decade has shown that abnormal activation of epithelial to mesenchymal transition (EMT… 
2010
2010
Alterations in the aqueous humor proteome in patients with Fuchs endothelial corneal dystrophy
Fuchs endothelial corneal dystrophy (FECD) is a progressive disorder characterized by corneal endothelial decompensation leading… 
Highly Cited
2009
Highly Cited
2009
ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression
In human hepatocellular carcinoma (HCC), epithelial to mesenchymal transition (EMT) correlates with aggressiveness of tumors and… 
Highly Cited
2006
Highly Cited
2006
Biomarker Discovery from Pancreatic Cancer Secretome Using a Differential Proteomic Approach*S
Quantitative proteomics can be used as a screening tool for identification of differentially expressed proteins as potential… 
Highly Cited
2006
Highly Cited
2006
ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells.
Highly Cited
2005
Highly Cited
2005
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers
The purpose of this study is to identify novel proteins released by cancer cells that are involved in extracellular matrix (ECM… 
Highly Cited
2002
Highly Cited
2002
Cloning, expression, and initial characterization of a novel cytokine-like gene family.
We report the identification and characterization of a novel cytokine-like gene family using structure-based methods to search… 
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