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FAF2 gene

Known as: KIAA0887, FAF2, Fas associated factor family member 2 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis
Objective— The cellular demand for cholesterol requires control of its biosynthesis by the mevalonate pathway. Regulation of… 
Highly Cited
2016
Highly Cited
2016
Peroxin-Dependent Targeting of a Lipid Droplet-Destined Membrane Protein to ER-subdomains
Lipid droplets (LDs) are endoplasmic reticulum (ER)-derived lipid storage organelles uniquely encapsulated by phospholipid… 
Highly Cited
2013
Highly Cited
2013
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover
UBXD8 is a membrane-embedded recruitment factor for the p97/VCP segregase that has been previously linked to endoplasmic… 
Highly Cited
2012
Highly Cited
2012
Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets
Apolipoprotein B-100 after lipidation is dislocated from the ER lumen to the cytoplasmic surface of lipid droplets for… 
2011
2011
Arteriovenous fistula: end‐to‐end or end‐to side anastomosis?
The purpose of the present study was to compare the end‐to‐end (ETEa) with the end‐to‐side (ETSa) anastomosis in patients… 
Review
2011
Review
2011
Endoscopic Transethmoidal and Transconjunctival Inferior Fornix Approaches for Repairing the Combined Medial Wall and Orbital Floor Blowout Fractures
Purpose: To assess the combination of an endoscopic transethmoidal approach (ETEA) and a transconjunctival inferior fornix… 
Highly Cited
2010
Highly Cited
2010
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
Fatty acids (FAs) are essential for cell survival, yet their overaccumulation causes lipotoxicity. To prevent lipotoxicity, cells… 
Highly Cited
2010
Highly Cited
2010
The RasGAP Proteins Ira2 and Neurofibromin Are Negatively Regulated by Gpb1 in Yeast and ETEA in Humans
ABSTRACT The neurofibromatosis type 1 (NF1) gene encodes the GTPase-activating protein (GAP) neurofibromin, which negatively… 
Highly Cited
2009
Highly Cited
2009
Targeting sequences of UBXD8 and AAM-B reveal that the ER has a direct role in the emergence and regression of lipid droplets
Lipid droplets are sites of neutral lipid storage thought to be actively involved in lipid homeostasis. A popular model proposes… 
2002
2002
Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.
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