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FAF2 gene

Known as: KIAA0887, FAF2, Fas associated factor family member 2 
 
National Institutes of Health

Papers overview

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2018
2018
UBXN3B positively regulates STING-mediated antiviral immune responses
The ubiquitin regulatory X domain-containing proteins (UBXNs) are likely involved in diverse biological processes. Their… Expand
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2016
2016
Peroxin-Dependent Targeting of a Lipid Droplet-Destined Membrane Protein to ER-subdomains
Lipid droplets (LDs) are endoplasmic reticulum (ER)-derived lipid storage organelles uniquely encapsulated by phospholipid… Expand
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2016
2016
Depressive symptoms can amplify embarrassment in essential tremor
BackgroundEmbarrassment can be a considerable problem for patients with essential tremor (ET) and is a major motivator for… Expand
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2015
2015
Hepatocyte-Specific Depletion of UBXD8 Induces Periportal Steatosis in Mice Fed a High-Fat Diet
We showed previously that UBXD8 plays a key role in proteasomal degradation of lipidated ApoB in hepatocarcinoma cell lines. In… Expand
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Highly Cited
2013
Highly Cited
2013
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.
UBXD8 is a membrane-embedded recruitment factor for the p97/VCP segregase that has been previously linked to endoplasmic… Expand
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2013
2013
UAS domain of Ubxd8 and FAF1 polymerizes upon interaction with long-chain unsaturated fatty acids.
Ubxd8, a multidomain protein sensor for long-chain unsaturated fatty acids (FAs), plays a crucial role to maintain cellular… Expand
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2012
2012
Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets
Apolipoprotein B-100 (ApoB) is the principal component of very low density lipoprotein. Poorly lipidated nascent ApoB is… Expand
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2010
2010
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis.
Fatty acids (FAs) are essential for cell survival, yet their overaccumulation causes lipotoxicity. To prevent lipotoxicity, cells… Expand
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2009
2009
Targeting sequences of UBXD8 and AAM-B reveal that the ER has a direct role in the emergence and regression of lipid droplets.
Lipid droplets are sites of neutral lipid storage thought to be actively involved in lipid homeostasis. A popular model proposes… Expand
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2002
2002
Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.
Analysis of patients with atopic dermatitis (AD) for differential expression of genes, as compared to normal individuals, will be… Expand
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