Estetrol

Known as: Estetrol [Chemical/Ingredient], 15 alpha-Hydroxyestriol, Estra-1,3,5(10)-triene-3,15,16,17-tetrol, (15alpha,16alpha,17beta)- 
A metabolite of ESTRIOL with a 15-alpha-hydroxyl group. Estetrol can be converted from estriol sulfate or DEHYDROEPIANDROSTERONE SULFATE by the fetal… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Estetrol (E4) is a recently described natural estrogen with four hydroxyl-groups that is synthesized exclusively during pregnancy… (More)
Is this relevant?
Review
2009
Review
2009
In this paper the potential clinical applications for the human fetal estrogen estetrol (E(4)) are presented based on recently… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
Background Currently, the synthetic steroid ethinylestradiol is the preferred estrogen in combined oral contraceptives. The aim… (More)
Is this relevant?
2008
2008
OBJECTIVE To evaluate the safety, tolerability, pharmacokinetics and effect on gonadotropins of a single escalating dose of… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
2008
2008
OBJECTIVES To determine whether human sex hormone binding globulin (SHBG) binds estetrol (E4), and to assess whether E4… (More)
  • figure 1
  • table 1
  • figure 2
Is this relevant?
2008
2008
OBJECTIVE To evaluate the efficacy of estetrol (E(4)) in alleviating hot flushes in an experimental animal model considered… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
Is this relevant?
2008
2008
OBJECTIVES To measure the oral bioavailability of estetrol (E(4)) in rats relative to its subcutaneous administration and to test… (More)
Is this relevant?
2008
2008
OBJECTIVE To evaluate the effect of estetrol (E(4)) on vaginal cornification and uterine wet weight in the ovariectomized rat… (More)
Is this relevant?
2008
2008
Estetrol (E4) is a pregnancy-specific D-ring metabolite of estradiol (E2) and estriol (E3) produced by the human fetal liver and… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The nuclear orphan receptor CAR (constitutively active receptor or constitutive androstane receptor) can be activated in response… (More)
Is this relevant?