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Epstein-Barr Nuclear Antigen 2

Known as: BYRF1, Epstein-Barr Virus Nuclear Antigen 2, EBV Nuclear Antigen 2 
Epstein-Barr nuclear antigen 2 (487 aa, ~55 kDa) is encoded by the Epstein-Barr virus EBNA2 gene. This protein is involved in the activation of host… 
National Institutes of Health

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2 relations
Genes, ViralVirus

Papers overview

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Highly Cited
2003
Highly Cited
2003
EBNA2 and Activated Notch Induce Expression of BATF
ABSTRACT The immortalization of human B lymphocytes by Epstein-Barr virus (EBV) requires the virus-encoded transactivator EBNA2… 
Highly Cited
2002
Highly Cited
2002
The Conserved Mynd Domain of BS69 Binds Cellular and Oncoviral Proteins through a Common PXLXP Motif*
BS69 is a transcriptional co-repressor protein and a potential tumor suppressor that binds to the adenoviral oncoprotein E1A. We… 
Highly Cited
1996
Highly Cited
1996
EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes
Although genetic and biochemical data indicate that the cell protein RBPJkappa is a mediator of EBNA-2 and EBNA-3C effects on… 
Highly Cited
1995
Highly Cited
1995
Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator
Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA-3C) is one of five viral nuclear proteins that are essential for EBV-induced… 
Highly Cited
1995
Highly Cited
1995
The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.
EBNA 2 (Epstein-Barr virus nuclear antigen 2) is an acidic transactivator essential for EBV transformation of B lymphocytes. We… 
Highly Cited
1994
Highly Cited
1994
EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1
The EBNA-2 protein is essential for the establishment of a latent Epstein-Barr virus (EBV) infection and for B-cell… 
Highly Cited
1993
Highly Cited
1993
EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif
EBNA-2 contributes to the establishment of Epstein-Barr virus (EBV) latency in B cells and to the resultant alterations in B-cell… 
Highly Cited
1991
Highly Cited
1991
An Epstein-Barr virus nuclear protein 2 domain essential for transformation is a direct transcriptional activator
Epstein-Barr virus nuclear protein 2 (EBNA-2) increases mRNA levels of specific viral and cellular genes through direct or… 
Highly Cited
1991
Highly Cited
1991
A transformation-incompetent, nuclear antigen 2-deleted Epstein-Barr virus associated with replicative infection.
Epstein-Barr virus (EBV) obtained directly from the oropharynx was used to detect viral DNA deleted for the EBV nuclear antigen 2… 
Highly Cited
1987
Highly Cited
1987
A bicistronic Epstein-Barr virus mRNA encodes two nuclear proteins in latently infected, growth-transformed lymphocytes
EBNA2 is a nuclear protein expressed in all cells latently infected with and growth transformed by Epstein-Barr virus (EBV… 
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