Epstein-Barr Nuclear Antigen 2

Known as: BYRF1, Epstein-Barr Virus Nuclear Antigen 2, EBV Nuclear Antigen 2 
Epstein-Barr nuclear antigen 2 (487 aa, ~55 kDa) is encoded by the Epstein-Barr virus EBNA2 gene. This protein is involved in the activation of host… (More)
National Institutes of Health

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Genes, ViralVirus

Papers overview

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2006
2006
Cellular target genes of Epstein-Barr virus nuclear antigen 2.
Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven B-cell growth transformation process… (More)
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Highly Cited
2005
Highly Cited
2005
Temporal relationship between elevation of epstein-barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis.
CONTEXT Infection with Epstein-Barr virus (EBV) has been associated with an increased risk of multiple sclerosis (MS), but the… (More)
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Highly Cited
2002
Highly Cited
2002
Epstein–Barr virus–associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2
Epstein–Barr virus (EBV) is etiologically linked to endemic Burkitt lymphoma (BL), but its contribution to lymphomagenesis… (More)
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Highly Cited
2001
Highly Cited
2001
Epstein-Barr virus antibodies and risk of multiple sclerosis: a prospective study.
CONTEXT Epidemiological studies suggest an association between infection with Epstein-Barr virus (EBV) and risk of multiple… (More)
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Highly Cited
1997
Highly Cited
1997
Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation.
Epstein-Barr virus (EBV) nuclear proteins EBNA-LP and EBNA-2 are the first two proteins expressed in latent infection of primary… (More)
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Highly Cited
1995
Highly Cited
1995
Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2.
Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) is a transcriptional activator that is essential for EBV-driven B cell… (More)
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Highly Cited
1994
Highly Cited
1994
Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein J kappa.
The Epstein-Barr virus (EBV) transactivator protein, termed Epstein-Barr virus nuclear antigen 2 (EBNA2), plays a critical role… (More)
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Highly Cited
1994
Highly Cited
1994
Gastric carcinoma: monoclonal epithelial malignant cells expressing Epstein-Barr virus latent infection protein.
In 1000 primary gastric carcinomas, 70 (7.0%) contained Epstein-Barr virus (EBV) genomic sequences detected by PCR and Southern… (More)
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Highly Cited
1991
Highly Cited
1991
Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease
The Epstein-Barr virus (EBV)-encoded latent gene products, latent membrane protein (LMP) and EBV nuclear antigen 2 (EBNA 2), seem… (More)
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Highly Cited
1987
Highly Cited
1987
Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.
Epstein-Barr virus (EBV) infection of EBV-negative Burkitt lymphoma (BL) cells induces some changes similar to those seen in… (More)
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