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Epstein-Barr Nuclear Antigen 2
Known as:
BYRF1
, Epstein-Barr Virus Nuclear Antigen 2
, EBV Nuclear Antigen 2
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Epstein-Barr nuclear antigen 2 (487 aa, ~55 kDa) is encoded by the Epstein-Barr virus EBNA2 gene. This protein is involved in the activation of host…
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National Institutes of Health
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Genes, Viral
Virus
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Highly Cited
2003
Highly Cited
2003
EBNA2 and Activated Notch Induce Expression of BATF
L. Johansen
,
C. Deppmann
,
+5 authors
E. Taparowsky
Journal of Virology
2003
Corpus ID: 23404901
ABSTRACT The immortalization of human B lymphocytes by Epstein-Barr virus (EBV) requires the virus-encoded transactivator EBNA2…
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Highly Cited
2002
Highly Cited
2002
The Conserved Mynd Domain of BS69 Binds Cellular and Oncoviral Proteins through a Common PXLXP Motif*
S. Ansieau
,
A. Leutz
Journal of Biological Chemistry
2002
Corpus ID: 42344932
BS69 is a transcriptional co-repressor protein and a potential tumor suppressor that binds to the adenoviral oncoprotein E1A. We…
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Highly Cited
1996
Highly Cited
1996
EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes
E. Johannsen
,
Cathy L. Miller
,
Steven R. Grossman
,
E. Kieff
Journal of Virology
1996
Corpus ID: 32812353
Although genetic and biochemical data indicate that the cell protein RBPJkappa is a mediator of EBNA-2 and EBNA-3C effects on…
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Highly Cited
1995
Highly Cited
1995
Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator
Dana R. Marshall
,
C. Sample
Journal of Virology
1995
Corpus ID: 13355758
Epstein-Barr virus (EBV) nuclear antigen 3C (EBNA-3C) is one of five viral nuclear proteins that are essential for EBV-induced…
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Highly Cited
1995
Highly Cited
1995
The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.
Xiao Tong
,
Ronny Drapkin
,
Danny Reinberg
,
Elliott Kieff
Proceedings of the National Academy of Sciences…
1995
Corpus ID: 23849823
EBNA 2 (Epstein-Barr virus nuclear antigen 2) is an acidic transactivator essential for EBV transformation of B lymphocytes. We…
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Highly Cited
1994
Highly Cited
1994
EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1
P. Ling
,
J. J. Hsieh
,
I. K. Ruf
,
D. Rawlins
,
S. Hayward
Journal of Virology
1994
Corpus ID: 24327982
The EBNA-2 protein is essential for the establishment of a latent Epstein-Barr virus (EBV) infection and for B-cell…
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Highly Cited
1993
Highly Cited
1993
EBNA-2 of herpesvirus papio diverges significantly from the type A and type B EBNA-2 proteins of Epstein-Barr virus but retains an efficient transactivation domain with a conserved hydrophobic motif
D. Paul
,
Ling
,
J. Ryon
,
S. Diane
,
HAYWARDl
Journal of Virology
1993
Corpus ID: 40928228
EBNA-2 contributes to the establishment of Epstein-Barr virus (EBV) latency in B cells and to the resultant alterations in B-cell…
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Highly Cited
1991
Highly Cited
1991
An Epstein-Barr virus nuclear protein 2 domain essential for transformation is a direct transcriptional activator
J. I. Cohen
,
E. Kieff
Journal of Virology
1991
Corpus ID: 7298196
Epstein-Barr virus nuclear protein 2 (EBNA-2) increases mRNA levels of specific viral and cellular genes through direct or…
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Highly Cited
1991
Highly Cited
1991
A transformation-incompetent, nuclear antigen 2-deleted Epstein-Barr virus associated with replicative infection.
J. Sixbey
,
Pamela S. Shirley
,
M. Sloas
,
N. Raab-Traub
,
V. Israele
Journal of Infectious Diseases
1991
Corpus ID: 9219495
Epstein-Barr virus (EBV) obtained directly from the oropharynx was used to detect viral DNA deleted for the EBV nuclear antigen 2…
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Highly Cited
1987
Highly Cited
1987
A bicistronic Epstein-Barr virus mRNA encodes two nuclear proteins in latently infected, growth-transformed lymphocytes
F. Wang
,
L. Petti
,
D. Braun
,
S. Seung
,
E. Kieff
Journal of Virology
1987
Corpus ID: 23360561
EBNA2 is a nuclear protein expressed in all cells latently infected with and growth transformed by Epstein-Barr virus (EBV…
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