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Eph Ligand Family 2 Protein, Mammalian

Known as: Mammalian ELF 2, Htk Ligand, ELF 2 Protein, Mammalian 
 
National Institutes of Health

Related topics

Related topics

2 relations
EFNB2 gene

Broader (1)

Ephrin-B2

Papers overview

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2019
2019
Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres
High-grade glioma (HGG, WHO Grade III–IV) accounts for the majority of adult primary malignant brain tumors. Failure of current… Expand
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2018
2018
mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility
Formin is one of the two major classes of actin binding proteins (ABPs) with nucleation and polymerization activity. However… Expand
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2015
2015
Small-molecule agonists of mammalian Diaphanous–related (mDia) formins reveal an effective glioblastoma anti-invasion strategy
Formin agonists impede the most dangerous aspect of glioblastoma—tumor spread into surrounding healthy tissue. Formin activation… Expand
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Highly Cited
2014
Highly Cited
2014
Lunapark stabilizes nascent three-way junctions in the endoplasmic reticulum
Significance In this study, we have identified an important role of mammalian Lnp1 (mLnp1) in stabilizing nascent three-way ER… Expand
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Highly Cited
2013
Highly Cited
2013
DUX4 Binding to Retroelements Creates Promoters That Are Active in FSHD Muscle and Testis
The human double-homeodomain retrogene DUX4 is expressed in the testis and epigenetically repressed in somatic tissues… Expand
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2013
2013
Small-molecule intramimics of formin autoinhibition: a new strategy to target the cytoskeletal remodeling machinery in cancer cells.
Although the cancer cell cytoskeleton is a clinically validated target, few new strategies have emerged for selectively targeting… Expand
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2013
2013
Therapeutics , Targets , and Chemical Biology Small-Molecule Intramimics of Formin Autoinhibition : A New Strategy to Target the Cytoskeletal RemodelingMachinery in Cancer Cells
Although the cancer cell cytoskeleton is a clinically validated target, few new strategies have emerged for selectively targeting… Expand
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2011
2011
Mitosis: Formin' an attachment
  • A. Schuldt
  • Nature Reviews Molecular Cell Biology
  • 2011
    • Corpus ID: 38771443
The mammalian diaphanousrelated formins (mDIAs), originally character ized for their ability to nucleate unbranched actin, can… Expand
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2009
2009
Mammalian Diaphanous (mDia) may be involved in the signal transduction of sphingosine‐1‐phosphate on developing actin stress fiber of human fibroblasts
Sphingosine 1‐phosphate (S1P) is a biologically active lipid mediator with many pivotal roles in the regulation of cell growth… Expand
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Highly Cited
2002
Highly Cited
2002
Mammalian APH-1 Interacts with Presenilin and Nicastrin and Is Required for Intramembrane Proteolysis of Amyloid-β Precursor Protein and Notch*
Presenilin and nicastrin are essential components of the γ-secretase complex that is required for the intramembrane proteolysis… Expand
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