Enediyne Antineoplastic Antibiotic

An enediyne antineoplastic antibiotic isolated from Streptomyces bacterial species or derived synthetically. After cycloaromatization, the enediyne… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
01219952018

Papers overview

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2018
2018
Dynemicin A is a member of a subfamily of enediyne antitumour antibiotics characterized by a 10-membered carbocycle fused to an… (More)
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2014
2014
Targeting to two or more objectives simultaneously has been pursued as a strategy to potentially increase the efficiency and… (More)
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2014
2014
The ability of the radiomimetic anti-tumor enediyne C-1027 to induce DNA inter-strand crosslinks (ICLs), in addition to the… (More)
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2009
2009
In the present study, the effects of lidamycin (LDM), a member of the enediyne antibiotic family, on two human multiple myeloma… (More)
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2007
2007
The enediyne chromoproteins are a class of potent antitumour antibiotics comprising a 1:1 complex of a protein and a… (More)
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2006
2006
C-1027 is an extremely potent antitumor agent that causes double-stranded DNA cleavages. It is a unique small molecule-protein… (More)
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2003
2003
Neocarzinostatin is the most studied member of the enediyne-chromoprotein family, and is clinically used as an antitumoral agent… (More)
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2001
2001
Treatment of cells with the enediyne C-1027 is highly efficient at inducing single- and double-strand DNA breaks. This agent is… (More)
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1996
1996
The reaction of bis-propargyl bromide enediyne 4 with weakly basic nucleophiles allows the facile synthesis of acyclic and… (More)
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1995
1995
BACKGROUND Enediyne chromoproteins are potent antitumor antibiotic agents. They consist of a labile nine-membered enediyne… (More)
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