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Enediyne Antineoplastic Antibiotic

An enediyne antineoplastic antibiotic isolated from Streptomyces bacterial species or derived synthetically. After cycloaromatization, the enediyne… Expand
National Institutes of Health

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2018
2018
Dynemicin A is a member of a subfamily of enediyne antitumor antibiotics characterized by a 10-membered carbocycle fused to an… Expand
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2009
2009
In recent years, members of the marine actinomycete genus Salinispora have proven to be a precious source of structurally diverse… Expand
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2009
2009
In the present study, the effects of lidamycin (LDM), a member of the enediyne antibiotic family, on two human multiple myeloma… Expand
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2007
2007
The enediyne chromoproteins are a class of potent antitumour antibiotics comprising a 1:1 complex of a protein and a… Expand
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2006
2006
[reaction: see text] Treatment of the benzannulated enediyne 11 with potassium tert-butoxide in refluxing toluene for 12 h… Expand
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2006
2006
C-1027 is an extremely potent antitumor agent that causes double-stranded DNA cleavages. It is a unique small molecule-protein… Expand
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2005
2005
[reaction: see text] A cyclopropenone-containing enediyne photoprecursor, 6-tert-butyldimethylsilyloxy-3-(alpha-hydroxybenzyl… Expand
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2003
2003
Neocarzinostatin is the most studied member of the enediyne-chromoprotein family, and is clinically used as an antitumoral agent… Expand
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2002
2002
The ruthenium(II) cation, [Cp*Ru(NCMe)3]OTf (4), triggers the Bergman cycloaromatization of acyclic endiynes at room temperature… Expand
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2001
2001
We report the syntheses, reactivities, and structure evaluations of a series of Cu(I) and Cu(II) metalloenediynes of conjugated 1… Expand
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