Endothelin A Receptor Antagonists

Known as: Antagonists, Endothelin A Receptor, Endothelin Receptor Type A Antagonist, Endothelin A Receptor Blockers 
A substance that blocks the binding of the endothelin-1 protein to its receptor. Endothelin-1 is a small molecule that causes changes in blood… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
0204019892017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Reactive astrocytes are thought to protect the penumbra during brain ischemia, but direct evidence has been lacking due to the… (More)
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Highly Cited
2006
Highly Cited
2006
Collecting duct (CD)-derived endothelin-1 (ET-1) inhibits renal Na reabsorption and its deficiency increases blood pressure (BP… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Endothelin-receptor blockade provides haemodynamic benefit in experimental and clinical heart failure. We aimed to… (More)
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Highly Cited
2004
Highly Cited
2004
Phenotypic and genotypic analyses of cutaneous melanoma have identified the endothelin B receptor (ET(B)R) as tumor progression… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND An activated endothelin (ET) system may be of pathophysiological relevance in human heart failure. We characterized… (More)
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1998
1998
Endothelin-1, unlike the selective endothelin ETB receptor agonist sarafotoxin S6c, causes nociception in the rat when injected… (More)
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Highly Cited
1996
Highly Cited
1996
Hepatic stellate cells are similar to tissue pericytes and have been shown to be contractile. In this study, we examined the… (More)
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Highly Cited
1995
Highly Cited
1995
The selective endothelin-A (ETA)-receptor antagonist BQ-123 has been shown to prevent chronic hypoxia-induced pulmonary… (More)
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Highly Cited
1994
Highly Cited
1994
We describe the characteristics of a potent and selective endothelin (ET) B-receptor antagonist, BQ-788 [N-cis-2,6… (More)
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Highly Cited
1994
Highly Cited
1994
Defects in the gene encoding the endothelin-B receptor produce aganglionic megacolon and pigmentary disorders in mice and humans… (More)
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