Ectodermal

CONTEXT Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy is known as a rare hereditary disease with classic triad… (More)

All ectodermal organs, e.g. hair, teeth, and many exocrine glands, originate from two adjacent tissue layers: the epithelium and… (More)

To determine the role of fibroblast growth factor (FGF) signalling from the apical ectodermal ridge (AER), we inactivated Fgf4… (More)

Neural crest cells, which generate peripheral nervous system and facial skeleton, arise at the neural plate/ectodermal border via… (More)

The molecular basis of X-linked recessive anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) has remained elusive… (More)

The composite structure of the mammalian skull, which forms predominantly via intramembranous ossification, requires precise pre… (More)

The p53 tumour suppressor is a transcription factor that regulates the progression of the cell through its cycle and cell death… (More)

Ectodermal dysplasias comprise over 150 syndromes of unknown pathogenesis. X–linked anhidrotic ectodermal dysplasia (EDA) is… (More)

The crumbs protein of Drosophila is an integral membrane protein, with 30 EGF-like and 4 laminin A G domain-like repeats in its… (More)

In Drosophila, the proneural genes of the achaete-scute complex encode transcriptional activators that can commit cells to a… (More)