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Early Rheumatoid Arthritis

Recent diagnosis of rheumatoid arthritis (usually within one to two years of onset) during which treatment may be more effective and possibly improve… 
National Institutes of Health

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3 relations
Connective and Soft TissueJointsRheumatoid Arthritis

Papers overview

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Highly Cited
2011
Highly Cited
2011
Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: observations from the Epidemiological Investigation…
OBJECTIVE To determine whether cigarette smoking influences the response to treatment in patients with early rheumatoid arthritis… 
Highly Cited
2011
Highly Cited
2011
A tight control treatment strategy aiming for remission in early rheumatoid arthritis is more effective than usual care treatment in daily clinical practice: a study of two cohorts in the Dutch…
There is strong evidence from clinical trials that a ‘treat to target’ strategy is effective in reaching remission in rheumatoid… 
Highly Cited
2011
Highly Cited
2011
Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis.
OBJECTIVE Adipose tissue can secrete soluble mediators (adipokines) with potent immune regulatory functions. Some adipokines have… 
Highly Cited
2006
Highly Cited
2006
Early rheumatoid arthritis is associated with a deficit in the CD4+CD25high regulatory T cell population in peripheral blood.
OBJECTIVE Our aim was to test the hypothesis that there is a deficit in the CD4+CD25high regulatory T-cell population in early… 
Highly Cited
2004
Highly Cited
2004
Prognostic markers of radiographic progression in early rheumatoid arthritis.
OBJECTIVE To identify prognostic markers that are predictive of progressive erosive disease in patients with early rheumatoid… 
Highly Cited
2001
Highly Cited
2001
Influence of sex, age, and menopausal state on the course of early rheumatoid arthritis.
OBJECTIVE To investigate the influences of the menopausal state, sex, and age on the course and outcome of rheumatoid arthritis… 
Highly Cited
1998
Highly Cited
1998
Joint destruction after glucocorticoids are withdrawn in early rheumatoid arthritis. Arthritis and Rheumatism Council Low Dose Glucocorticoid Study Group.
OBJECTIVE Prednisolone reduced the progression of joint destruction over 2 yr in early, active rheumatoid arthritis. The response… 
Highly Cited
1995
Highly Cited
1995
Positive selection in autoimmunity: Abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis
A novel ‘multistep molecular mimicry’ mechanism for induction of rheumatoid arthritis (RA) by bacterial antigens that activate T… 
Highly Cited
1992
Highly Cited
1992
Biannual radiographic assessments of hands and feet in a three-year prospective followup of patients with early rheumatoid arthritis.
In a prospective followup study of 147 patients with rheumatoid arthritis of recent onset, we assessed the progression of… 
Highly Cited
1991
Highly Cited
1991
Predictors of fractures in early rheumatoid arthritis.
Three hundred ninety-five patients with rheumatoid arthritis (mean age 49 years) were followed for an average of 6.7 years, and… 
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