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EXTL1 gene

Known as: Exostoses (Multiple)-Like 1 Gene, alpha-N-acetylglucosaminyltransferase II, exostosin-L 
This gene plays a role in carbohydrate metabolism and the biosynthesis of heparin/heparin sulfate.
National Institutes of Health

Related topics

Related topics

6 relations
EXT1 geneEXT2 geneEXTL1 protein, humanHeparan Sulfate Biosynthesis
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EXTL1 wt Allele

Papers overview

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2015
2015
Impact of the Asian monsoon on the extratropical lower stratosphere: trace gas observations during TACTS over Europe 2012
Abstract. The transport of air masses originating from the Asian monsoon anticyclone into the extratropical upper troposphere and… Expand
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Highly Cited
2010
Highly Cited
2010
Multimodel assessment of the upper troposphere and lower stratosphere: Extratropics
A multimodel assessment of the performance of chemistry-climate models (CCMs) in the extratropical upper troposphere/lower… Expand
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Highly Cited
2007
Highly Cited
2007
A Lagrangian perspective of the tropopause and the ventilation of the lowermost stratosphere
Back trajectories driven by large-scale analyzed wind fields are used to investigate troposphere to stratosphere transport (TST… Expand
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Highly Cited
2007
Highly Cited
2007
Contribution of EXT1, EXT2, and EXTL3 to Heparan Sulfate Chain Elongation*
The exostosin (EXT) family of genes encodes glycosyltransferases involved in heparan sulfate biosynthesis. Five human members of… Expand
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Highly Cited
2001
Highly Cited
2001
Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis
The tumor suppressors EXT1 and EXT2 are associated with hereditary multiple exostoses and encode bifunctional… Expand
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Highly Cited
2000
Highly Cited
2000
EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis
Hereditary multiple exostoses (HME) is a genetically heterogeneous disease characterized by the development of bony protuberances… Expand
Highly Cited
1999
Highly Cited
1999
Deletion mapping of chromosomal region 1p32‐pter in primary breast cancer
Distal alterations of the short arm of chromosome 1 are among the most frequent cytogenetic abnormalities in human breast… Expand
Highly Cited
1998
Highly Cited
1998
Identification of a third EXT-like gene (EXTL3) belonging to the EXT gene family.
Two homologous genes, EXT1 and EXT2, responsible for the development of benign multiple cartilagenous bone tumors (exostoses) on… Expand
Highly Cited
1997
Highly Cited
1997
Identification and Characterization of a Novel Member of the EXT Gene Family, EXTL2
Recently, two homologous genes, EXT1 and EXT2, with a putative tumor suppressor function have been described. Mutations in both… Expand
Highly Cited
1997
Highly Cited
1997
Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family.
Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by multiple bony outgrowths from the… Expand
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