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EXOC4 gene

Known as: MGC27170, SEC8, EXOCYST COMPLEX COMPONENT 4 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Probing Functional Changes in Exocyst Configuration with Monoclonal Antibodies
Spatial regulation of exocytosis relies on the exocyst, a hetero-octameric protein complex that tethers vesicles to fusion sites… 
2015
2015
SNAP23/25 and VAMP2 mediate exocytic event of transferrin receptor-containing recycling vesicles
ABSTRACT We recently showed that Rab11 is involved not only in formation of recycling vesicles containing the transferrin (Tfn… 
2014
2014
Knockdown of Sec8 promotes cell‐cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins
p21Cip1 protein inhibits the activity of cyclins at the G1 checkpoint and influences transition of cells from the G1 to the S… 
2014
2014
A Role for Exocyst in Maturation and Bactericidal Function of Staphylococci‐Containing Endothelial Cell Phagosomes
Bacteria that invade human endothelial cells can be efficiently eliminated in phagolysosomes. We investigated the role of vesicle… 
2013
2013
Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases
PurposeSec8, a component of the exocyst complex, has been implicated in tethering of secretory vesicles to specific regions on… 
2012
2012
Exocyst subunits are involved in isoproterenol-induced amylase release from rat parotid acinar cells.
Exocytosis of secretory granules in parotid acinar cells requires multiple events: tethering, docking, priming, and fusion with a… 
2011
2011
Pob1 Ensures Cylindrical Cell Shape by Coupling Two Distinct Rho Signaling Events During Secretory Vesicle Targeting
Proper cell morphogenesis requires the co‐ordination of cell polarity, cytoskeletal organization and vesicle trafficking. The… 
2009
2009
Insulin stimulates the phosphorylation of the exocyst protein Sec8 in adipocytes.
The signal transduction pathway leading from the insulin receptor to stimulate the fusion of vesicles containing the glucose… 
2006
2006
A role for Sec8 in oligodendrocyte morphological differentiation
In the central nervous system, oligodendrocytes synthesize vast amounts of myelin, a multilamellar membrane wrapped around axons… 
1997
1997
Characterization of a cDNA encoding a subunit of the rat brain rsec6/8 complex.
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