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Germline mutations of DNA double-strand break (DSB) response and repair genes that drive tumorigenesis could be a major cause of… Expand Purpose Germline mutations within melanoma susceptibility genes are present only in minority of melanoma patients and it is… Expand The Exo5 family consists of bi-directional, single-stranded DNA-specific exonucleases that contain an iron-sulfur cluster as a… Expand SUMMARY DNA damage repair (DDR) pathways modulate cancer risk, progression, and therapeutic response. We systematically analyzed… Expand Testicular germ cell tumors (TGCTs) are a clinically and pathologically heterogeneous disease, and little is known of its genetic… Expand Background: Deoxyribonucleases are key DNA metabolic enzymes, but their functions remain ill defined. Results: Human EXO5 is a… Expand Rhizobial lipopolysaccharide (LPS) is required to establish an effective symbiosis with its host plant. An exo5 mutant of… Expand ABSTRACT Yeast exonuclease 5 is encoded by the YBR163w (DEM1) gene, and this gene has been renamed EXO5. It is distantly related… Expand Two strains of exopolysaccharide defective mutants(ZJ4,ZJ6)were screened out of transposon mutant libraries.Arbitrary PCR was… Expand Analysis of two exopolysaccharide-deficient mutants of Rhizobium leguminosarum, RBL5808 and RBL5812, revealed independent Tn5… Expand