EX 527

Known as: EX-527, EX527 cpd 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
05101520062017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Sirtuins are protein deacetylases regulating metabolism and stress responses. The seven human Sirtuins (Sirt1-7) are attractive… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Inflammation participates centrally in all stages of atherosclerosis (AS), which begins with inflammatory changes in the… (More)
Is this relevant?
2012
2012
The Foxp3 transcription factor is the master regulator of regulatory T cell (Treg) differentiation and function. Its activity is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2012
2012
Oxidative stress and mitochondrial dysfunction are involved in the pathogenesis of diabetic nephropathy (DN). Resveratrol has… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Activation of Nrf2 by covalent modifications that release it from its inhibitor protein Keap1 has been extensively documented. In… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2011
2011
Sirtuin 1 (Sirt1), a class III histone/protein deacetylase, is central to cellular metabolism, stress responses, and aging, but… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2011
2011
Resveratrol, a polyphenol compound, is known for its effects on energy homeostasis. With properties of energy sensors mediating… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
2010
2010
The bone protective effects of resveratrol have been demonstrated in several osteoporosis models while the underlying mechanism… (More)
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Cortactin binds F-actin and promotes cell migration. We showed earlier that cortactin is acetylated. Here, we identify SIRT1 (a… (More)
  • figure 1
  • figure 1
  • figure 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Human SIRT1 is an enzyme that deacetylates the p53 tumor suppressor protein and has been suggested to modulate p53-dependent… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?