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EX 527

Known as: EX-527, EX527 cpd 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Dynamic aspects of melatonin's actions merit increasing future attention. This concerns particularly entirely different effects… Expand
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Highly Cited
2013
Highly Cited
2013
Significance Sirtuin enzymes regulate metabolism and stress responses through deacetylation of specific protein lysine residues… Expand
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Highly Cited
2013
Highly Cited
2013
Inflammation participates centrally in all stages of atherosclerosis (AS), which begins with inflammatory changes in the… Expand
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Highly Cited
2013
Highly Cited
2013
Autosomal-dominant polycystic kidney disease (ADPKD) is caused by mutations in either PKD1 or PKD2 and is characterized by the… Expand
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Highly Cited
2011
Highly Cited
2011
Sirtuin 1 (Sirt1), a class III histone/protein deacetylase, is central to cellular metabolism, stress responses, and aging, but… Expand
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Highly Cited
2010
Highly Cited
2010
Activation of Nrf2 by covalent modifications that release it from its inhibitor protein Keap1 has been extensively documented. In… Expand
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Highly Cited
2010
Highly Cited
2010
Sirt1 has been associated with various effects of calorie restriction, including an increase in lifespan. Here we show in mice… Expand
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Highly Cited
2010
Highly Cited
2010
Resveratrol, a polyphenol compound, is known for its effects on energy homeostasis. With properties of energy sensors mediating… Expand
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Highly Cited
2009
Highly Cited
2009
Cortactin binds F-actin and promotes cell migration. We showed earlier that cortactin is acetylated. Here, we identify SIRT1 (a… Expand
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Highly Cited
2006
Highly Cited
2006
Human SIRT1 is an enzyme that deacetylates the p53 tumor suppressor protein and has been suggested to modulate p53-dependent… Expand
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