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J. Neurochem. (2010) 115, 1363–1373.
EUK-189, a salen-manganese complex and superoxide dismutase/catalase mimetic, was administered subcutaneously (sc; 30 or 70 mg/kg… Expand Extensive epidemiological data in humans and studies in animal models of Parkinson's disease (PD) suggest that sporadic forms of… Expand BACKGROUND AND PURPOSE
The purpose of the current study was to elucidate the protective/mitigating effects of a SOD-catalase… Expand Overexpression of the c-Met/hepatocyte growth factor receptor(HGF-R) proto-oncogene and abnormal generation of intracellular… Expand One postulated mechanism for the reduction in stress tolerance with aging is a decline in the regulation of stress-responsive… Expand Exposure of mice to the herbicide paraquat has been demonstrated to result in the selective loss of dopaminergic neurons of the… Expand A reduction in stress tolerance is a hallmark of the aging process, and the lowered functional capacity observed in aged… Expand Oxidative stress has been implicated in cognitive impairment in both old experimental animals and aged humans. This implication… Expand Neuronal apoptosis induced by staurosporine (STS) involves multiple cellular and molecular events, such as the production of… Expand