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ETV6 wt Allele

Known as: ETV6, ETS Variant Gene 6 (TEL Oncogene) wt Allele, ETS Variant Gene 6 
Human ETV6 wild-type allele is located in the vicinity of 12p13 and is approximately 246 kb in length. This allele, which encodes transcription… 
National Institutes of Health

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7 relations
12p13ETV6 protein, humanHematopoiesisHomo sapiens

Broader (1)

ETV6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
ETV6 Regulates Pax5 Expression in Early B Cell Development
Recent studies from our group and others have revealed a role for ETV6 germline mutations in the predisposition to ALL. Although… 
2015
2015
Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia
2015
2015
Expression of ETV6/TEL is associated with prognosis in non-small cell lung cancer.
The ETV6/TEL gene is a member of the ETS family of transcription factors that has been mainly studied in hematological diseases… 
2015
2015
Expression of ETV 6 / TEL is associated with prognosis in non-small cell lung cancer
The ETV6/TEL gene is a member of the ETS family of transcription factors that has been mainly studied in hematological diseases… 
2014
2014
Dissecting the role of the ETV6 transcriptional regulator in development and disease
This study studied the ETV6 gene using zebrafish as a model. The work demonstrated that ETV6 was important for the development of… 
2008
2008
Connections Between ETV6-Modulated Genes: Identification of Shared Features
Accumulating genetic and functional evidence point to ETV6 as being the tumour suppressor gene targeted by the deletions at… 
Highly Cited
2005
Highly Cited
2005
The hypereosinophilic syndrome: fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases.
BACKGROUND AND OBJECTIVES According to WHO criteria, the idiopathic hypereosinophilic syndrome (HES) is defined as persistent… 
Review
1998
Review
1998
The second ETV6 allele is not necessarily deleted in acute leukemias with a ETV6/ABL fusion
The ETV6 (TEL) locus at chromosome band 12p13 is a major site of translocations in acute leukemia, particularly in childhood… 
1997
1997
Analysis of ETV6 and ETV6‐AML1 proteins in acute lymphoblastic leukaemia
The t(12;21) is a recurring chromosomal abnormality in acute lymphoblastic leukaemias (ALLs) which results in the production of… 
Review
1996
Review
1996
ETV6 gene rearrangements in hematopoietic malignant disorders.
Chromosomal abnormalities involving the short arm of chromosome 12 have been frequently observed in a broad spectrum of… 
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