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EPC2407

Known as: Microtubule Inhibitor EPC2407 
 
National Institutes of Health

Papers overview

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2017
2017
Tubulin-targeting compounds have a broad anticancer spectrum and are an important class of chemotherapeutic agents. Due to the… Expand
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2016
2016
PurposeThe goal of the present study was to examine the safety and efficacy of the vascular disrupting agent (VDA) EPC2407… Expand
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2015
2015
The high mortality rate associated with castration-resistant prostate cancer (CRPC) underscores the need for improving… Expand
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Review
2014
Review
2014
Anaplastic thyroid cancer (ATC) is one of the most deadly cancers in humans. Searching a PubMed database, studies published… Expand
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Review
2009
Review
2009
Many cancer cells are known to have defects in the apoptosis machinery. Therefore identification of compounds that can activate… Expand
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2009
2009
3569 Background: EPC2407 is a 4-aryl-chromene single isomer microtubulin inhibitor with vascular disrupting and apoptotic… Expand
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2008
2008
2531 Background: EPC2407 is a 4-aryl-chromene single isomer microtubulin inhibitor which in preclinical models showed antitumor… Expand
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2007
2007
B4 EPC2407 is a small molecule new chemical entity vascular disruption agent (VDA) which also induces apoptosis. The biology… Expand
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Review
2007
Review
2007
  • Sui Xiong Cai
  • Recent patents on anti-cancer drug discovery
  • 2007
  • Corpus ID: 25873315
Vascular disrupting agents (VDAs) are a new class of potential anticancer drugs that selectively destroy tumor vasculature and… Expand
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