EPAS1 gene

Known as: HLF, MOP2, Endothelial PAS Domain Protein 1 Gene 
This gene plays a role in the cellular response to hypoxia.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
As modern humans migrated out of Africa, they encountered many new environmental conditions, including greater temperature… (More)
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Highly Cited
2013
Highly Cited
2013
Pheochromocytomas (PCCs) and paragangliomas (PGLs) are chromaffin-cell tumors that arise from the adrenal medulla and extra… (More)
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Highly Cited
2010
Highly Cited
2010
Osteoarthritic cartilage destruction is caused by an imbalance between anabolic and catabolic factors. Here, we show that hypoxia… (More)
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Highly Cited
2010
Highly Cited
2010
Chondrocyte hypertrophy followed by cartilage matrix degradation and vascular invasion, characterized by expression of type X… (More)
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2007
2007
AIM To evaluate the prognostic significance of HIF-2alpha/EPAS1 expression in hepatocellular carcinoma (HCC). METHODS Surgical… (More)
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2004
2004
Adipose differentiation is regulated by several transcription factors, such as the CAAT/enhancer-binding protein family and… (More)
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Highly Cited
2003
Highly Cited
2003
Hypoxic stress plays a role in pathophysiologic states such as myocardial infarction and cerebral vascular events as well as in… (More)
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Highly Cited
1998
Highly Cited
1998
Mice lacking the hypoxia-inducible transcription factor EPAS1 die at mid-gestation. Despite normal morphological development of… (More)
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Highly Cited
1998
Highly Cited
1998
The HIF1A gene encodes the HIF-1alpha subunit of hypoxia-inducible factor 1, a transcription factor that is essential for… (More)
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Highly Cited
1997
Highly Cited
1997
Here we describe the cloning and characterization of a PAS domain transcription factor termed endothelial PAS-1 (EPAS1). This… (More)
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