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EPAS1 gene

Known as: HLF, MOP2, Endothelial PAS Domain Protein 1 Gene 
This gene plays a role in the cellular response to hypoxia.
National Institutes of Health

Related topics

Related topics

6 relations
Cellular Stress ResponseHomo sapiensTranscriptional Regulationdna binding

Papers overview

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2016
2016
Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis
One of the earliest requirements for the formation of a solid tumor is the establishment of an adequate blood supply. Clear cell… 
Review
2015
Review
2015
HIF2a inhibitors for the treatment of VHL disease
Patients with von Hippel-Lindau (VHL) disease possess a germline mutation in the VHL tumor suppressor gene that confers a life… 
2014
2014
The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling.
PURPOSE To define the role of hypoxia and vascular endothelial growth factor (VEGF) in modifying the pattern, density, and… 
2012
2012
The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma.
In follow-up of a recent genome-wide association study (GWAS) that identified a locus in chromosome 2p21 associated with risk for… 
2007
2007
MODULATOR OF PIN genes control steady-state levels of Arabidopsis PIN proteins.
Polar transport of the phytohormone auxin controls numerous growth responses in plants. Molecular characterization of auxin… 
Highly Cited
2005
Highly Cited
2005
The EPAS1 gene influences the aerobic–anaerobic contribution in elite endurance athletes
AbsractEPAS1 is a gene involved in complex oxygen sensing. It is expressed in microvascular endothelial cells, lung epithelial… 
2004
2004
Expression of HIF-2alpha/EPAS1 in hepatocellular carcinoma.
AIM To investigate the expression of hypoxia-inducible factor (HIF)-2alpha/endothelial PAS domain protein1 (EPAS1) in… 
2002
2002
Endothelial PAS domain protein 1 (EPAS1) induces adrenomedullin gene expression in cardiac myocytes: role of EPAS1 in an inflammatory response in cardiac myocytes.
Endothelial PAS domain protein 1 (EPAS1) has been identified as a member of the basic helix-loop-helix (bHLH)-PAS protein family… 
1999
1999
Cloning and expression pattern of EPAS1 in the chicken embryo
Highly Cited
1995
Highly Cited
1995
MOP2 (SLA2) Affects the Abundance of the Plasma Membrane H+-ATPase of Saccharomyces cerevisiae(*)
The abundance of yeast plasma membrane H+-ATPase on the cell surface is tightly regulated. Modifier of pma1 (mop) mutants were… 
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