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EO 9

Known as: EO9, EO-9, E O9 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

apaziquone

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase
Abstract.Purpose: Bioreductive antitumor agents are an important class of anticancer drugs that include the clinically used drug… 
Highly Cited
2001
Highly Cited
2001
Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: structure-activity relationships for cytotoxicity and antitumor activity.
A large number of aziridinyl quinones represented by series 1-9 were studied with respect to their DT-diaphorase substrate… 
2001
2001
Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species.
Review
1996
Review
1996
Development, pharmacology, role of DT-diaphorase and prospects of the indoloquinone EO9.
1996
1996
Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9. EORTC Early Clinical Trials Group.
1994
1994
Enhancement of interstitial photodynamic therapy by mitomycin C and EO9 in a mouse tumour model
The tumoricidal effect of interstitial photodynamic therapy (IPDT) using Photofrin was found to increase when combined with the… 
1993
1993
Cytotoxic effects of anticancer agents on subconfluent and multilayered postconfluent cultures.
1992
1992
The role of human and rodent DT-diaphorase in the reductive metabolism of hypoxic cell cytotoxins.
1992
1992
Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9.
1992
1992
Pharmacokinetics, distribution, and metabolism of the novel bioreductive alkylating indoloquinone EO9 in rodents.
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