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Heritable connective tissue diseases are a highly heterogeneous family of over 200 disorders that affect the extracellular matrix… Expand Objective—Emilin-1 is a protein of elastic extracellular matrix involved in blood pressure (BP) control by negatively affecting… Expand The evidence that EMILIN1 (Elastic Microfibril Interface Located proteIN) deficiency in Emilin1−/− mice caused dermal and… Expand BACKGROUND
Primary lymphedema, the accumulation of protein-rich fluid in the interstitial space, is the clinical manifestation of… Expand TGF-beta proteins are main regulators of blood vessel development and maintenance. Here, we report an unprecedented link between… Expand Mice deficient in Emilin1, an extracellular growth factor expressed in blood vessels, have hypertension. This observation… Expand The rejection of organs transplanted between phylogenetically disparate animals such as pigs and primates is thought to be… Expand The protein gp115 is an exocellular yeast glycoprotein modified by O- and N-glycosylation and attached to the plasma membrane… Expand This paper reports a phenotypic characterization of ggp1 mutants. The cloned GGP1 (GAS1) gene, which encodes a major GPI-anchored… Expand gp115 is a N- and O-glycosylated protein of Saccharomyces cerevisiae. It is also modified by addition of… Expand