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EMD 55900

Known as: EMD 55 900, Mab 425 
A murine monoclonal antibody targeting the epidermal growth factor receptor (EGFR) exhibiting anti-tumor activity. EMD 55900 antibody binds to the… 
National Institutes of Health

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antigen binding

Papers overview

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2004
2004
Dose-dependent access of murine anti-epidermal growth factor receptor monoclonal antibody to tumor cells in patients with advanced laryngeal and hypopharyngeal carcinoma
The murine IgG2a monoclonal antibody (mAb) EMD 55900 was produced against the human epidermoid carcinoma cell line A431, with… 
2003
2003
Carcinomas unresponsive to either cisplatinum or anti-EGFR therapy can be growth inhibited by combination therapy of both agents.
BACKGROUND Previously we demonstrated that the antitumor efficacy of monoclonal antibodies against the EGFR (epidermal growth… 
2002
2002
Anti‐epidermal growth factor receptor‐antibody therapy for treatment of breast cancer
Recent studies demonstrated that tumors overexpressing the epidermal growth factor receptor (EGF‐R, erbB‐1) are associated with… 
2001
2001
Tumor necrosis factor alpha sensitizes low epidermal growth factor receptor (EGFR)-expressing carcinomas for anti-EGFR therapy.
Analysis of 1,060 xenotransplants derived from cancer cell lines as wel as spontaneously occurring tumors from the larynx… 
2001
2001
Tumor Necrosis Factor a Sensitizes Low Epidermal Growth Factor Receptor ( EGFR )-expressing Carcinomas for Anti-EGFR Therapy 1
Analysis of 1060 xenotransplants derived from cancer cell lines as well as spontaneously occurring tumors from the larynx… 
1997
1997
Growth inhibition of human papillary thyroid carcinoma cells and multicellular spheroids by anti-EGF-receptor antibody.
EGF has been reported to stimulate thyroid cell proliferation. In the present study we investigated the effects of anti-EGF-R… 
1994
1994
Improved uptake of 125i-mab 425 into high grade glioma cells by pretreatment with chloroquine and/or unlabeled mouse IGG: Possible therapeutic applications
1993
1993
Finite proliferative lifespanin vitro of a human breast cancer cell strain isolated from a metastatic lymph node
SummaryWe recently described culture conditions that allow proliferation of metastatic human breast cancer cells from biopsy… 
1993
1993
Biochemical and immunohistochemical detection of the epidermal growth-factor receptor (EGF-R) in breast-tumor specimens.
Analyses of the level of expression of the epidermal growth factor receptor (EGF-R) of breast cancer tumors may add independent… 
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