EM-1745
National Institutes of Health
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Oestradiol is a well-characterized sex hormone that stimulates breast cancer and other oestrogen-related diseases. 17beta…
Endocrine therapies are widely used for the treatment of estrogen-sensitive diseases. 17β-hydroxysteroid dehydrogenase type 1 (17…
[structure: see text] The inhibitor of type 1 17beta-hydroxysteroid dehydrogenase EM-1745 (1) exhibits affinity for both the…
Human estrogenic 17β‐hydroxysteroid dehydrogenase (17β‐HSD type 1) catalyzes the final step in the synthesis of active estrogens…