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ELMO2 gene

Known as: CED12, KIAA1834, ELMO2 
 
National Institutes of Health

Related topics

Related topics

3 relations
ELMO1 geneELMO1 wt AlleleELMO3 gene

Papers overview

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2018
2018
HGF-induced formation of the MET–AXL–ELMO2–DOCK180 complex promotes RAC1 activation, receptor clustering, and cancer cell migration and invasion
The MET proto-oncogene–encoded receptor tyrosine kinase (MET) and AXL receptor tyrosine kinase (AXL) are independently operating… Expand
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2016
2016
Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling.
Vascular malformations are non-neoplastic expansions of blood vessels that arise due to errors during angiogenesis. They are a… Expand
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2015
2015
An ELMO2-RhoG-ILK network modulates microtubule dynamics
Complexes that contain ELMO2, RhoG, and integrin-linked kinase are required to maintain microtubule stability. Mechanistically… Expand
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2014
2014
Axl Phosphorylates Elmo Scaffold Proteins To Promote Rac Activation and Cell Invasion
ABSTRACT The receptor tyrosine kinase Axl contributes to cell migration and invasion. Expression of Axl correlates with… Expand
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2014
2014
Essential Role of Elmo1 in Dock2-Dependent Lymphocyte Migration
Elmo1 and Elmo2 are highly homologous cytoplasmic adaptor proteins that interact with Dock family guanine nucleotide exchange… Expand
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2009
2009
Integrin-linked kinase interactions with ELMO2 modulate cell polarity.
Cell polarization is a key prerequisite for directed migration during development, tissue regeneration, and metastasis. Integrin… Expand
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Highly Cited
2008
Highly Cited
2008
Dock4 regulates dendritic development in hippocampal neurons
Dendrite development is required for establishing proper neuronal connectivity. Rho‐family small GTPases have been reported to… Expand
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Highly Cited
2007
Highly Cited
2007
ELMOD2 Is an Arl2 GTPase-activating Protein That Also Acts on Arfs*
Regulatory GTPases in the Ras superfamily employ a cycle of alternating GTP binding and hydrolysis, controlled by guanine… Expand
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2006
2006
Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain
ELMO is an upstream regulator of the Rho family small GTPase Rac. We investigated the distributions of mRNAs of two subtypes of… Expand
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Highly Cited
2001
Highly Cited
2001
CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration
The C. elegans genes ced-2, ced-5, and ced-10, and their mammalian homologs crkII, dock180, and rac1, mediate cytoskeletal… Expand
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