ELMO2 gene

Known as: CED12, KIAA1834, ELMO2 
 
National Institutes of Health

Related topics

Related topics

3 relations
ELMO1 geneELMO1 wt AlleleELMO3 gene

Papers overview

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2016
2016
Loss-of-Function Mutations in ELMO2 Cause Intraosseous Vascular Malformation by Impeding RAC1 Signaling.
Vascular malformations are non-neoplastic expansions of blood vessels that arise due to errors during angiogenesis. They are a… Expand
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2016
2016
Involvement of Tiam1, RhoG and ELMO2/ILK in Rac1-mediated phagocytosis in human trabecular meshwork cells.
We previously demonstrated that an αvβ5 integrin/FAK- mediated pathway regulated the phagocytic properties of human trabecular… Expand
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2016
2016
Elmo2 Is a Regulator of Insulin-dependent Glut4 Membrane Translocation.
Elmo2, a member of the Elmo protein family, has been implicated in the regulation of Rac1 and Akt activation. Recently, we found… Expand
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2015
2015
An ELMO2-RhoG-ILK network modulates microtubule dynamics
ELMO2 belongs to a family of scaffold proteins involved in phagocytosis and cell motility. ELMO2 can simultaneously bind integrin… Expand
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2015
2015
Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion.
The receptor tyrosine kinase Axl contributes to cell migration and invasion. Expression of Axl correlates with metastatic… Expand
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2009
2009
Integrin-linked kinase interactions with ELMO2 modulate cell polarity.
Cell polarization is a key prerequisite for directed migration during development, tissue regeneration, and metastasis. Integrin… Expand
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2008
2008
Dock4 regulates dendritic development in hippocampal neurons.
Dendrite development is required for establishing proper neuronal connectivity. Rho-family small GTPases have been reported to… Expand
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2007
2007
ELMOD2 is an Arl2 GTPase-activating protein that also acts on Arfs.
Regulatory GTPases in the Ras superfamily employ a cycle of alternating GTP binding and hydrolysis, controlled by guanine… Expand
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2006
2006
Differential distribution of ELMO1 and ELMO2 mRNAs in the developing mouse brain
ELMO is an upstream regulator of the Rho family small GTPase Rac. We investigated the distributions of mRNAs of two subtypes of… Expand
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Highly Cited
2001
Highly Cited
2001
CED-12/ELMO, a Novel Member of the CrkII/Dock180/Rac Pathway, Is Required for Phagocytosis and Cell Migration
The C. elegans genes ced-2, ced-5, and ced-10, and their mammalian homologs crkII, dock180, and rac1, mediate cytoskeletal… Expand
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