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ELF5 gene

Known as: E74-LIKE FACTOR 5, ESE2, ELF5 
National Institutes of Health

Papers overview

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2015
2015
Elf5 inhibits TGF‐β‐driven epithelial‐mesenchymal transition in prostate cancer by repressing SMAD3 activation
The epithelial‐mesenchymal transition (EMT) has been associated with the acquisition of migration, invasiveness, and metastasis… 
2014
2014
Establishment of bovine trophoblast stem-like cells from in vitro-produced blastocyst-stage embryos using two inhibitors.
The trophoblast (TR) is the first to differentiate during mammalian embryogenesis and play a pivotal role in the development of… 
Highly Cited
2013
Highly Cited
2013
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
Progesterone-RankL paracrine signaling has been proposed as a driver of stem cell expansion in the mammary gland, and Elf5 is… 
Highly Cited
2009
Highly Cited
2009
Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5.
Highly Cited
2008
Highly Cited
2008
The Ets transcription factor Elf5 specifies mammary alveolar cell fate.
Hormonal cues regulate mammary development, but the consequent transcriptional changes and cell fate decisions are largely… 
Highly Cited
2007
Highly Cited
2007
Elf5 is an epithelium‐specific, fibroblast growth factor–sensitive transcription factor in the embryonic lung
Fibroblast growth factor (FGF) signaling has been shown to be essential for many aspects of normal lung development. To determine… 
Review
2006
Review
2006
Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium
Massive tissue remodelling occurs within the mammary gland during pregnancy, resulting in the formation of lobuloalveoli that are… 
Highly Cited
2006
Highly Cited
2006
Biochemical and NMR Study on the Competition between Proteins SC35, SRp40, and Heterogeneous Nuclear Ribonucleoprotein A1 at the HIV-1 Tat Exon 2 Splicing Site*
The human immunodeficiency virus, type 1, Tat protein plays a key role in virus multiplication. Because of its apoptotic property… 
Highly Cited
2005
Highly Cited
2005
Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation
Elf5 is an epithelial‐specific ETS factor. Embryos with a null mutation in the Elf5 gene died before embryonic day 7.5… 
2004
2004
A major site of expression of the ets transcription factor Elf5 is epithelia of exocrine glands
Elf5 belongs to the ets family of transcription factors and was cloned by homology in the DNA binding domain to the related… 
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