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ELF5 gene
Known as:
E74-LIKE FACTOR 5
, ESE2
, ELF5
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Loss of ELF5–FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling
Snahlata Singh
,
Sushil Kumar
,
+13 authors
R. Chakrabarti
Nature Cell Biology
2020
Corpus ID: 215750137
Triple-negative breast cancer (TNBC) is characterized by a high degree of immune infiltrate in the tumour microenvironment, which…
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Highly Cited
2015
Highly Cited
2015
Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks
P. Latos
,
Arnold R. Sienerth
,
+7 authors
M. Hemberger
Genes & Development
2015
Corpus ID: 32216563
Latos et al. demonstrate that precise levels of Elf5 are critical for normal expansion of the trophoblast stem cell (TSC…
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Highly Cited
2013
Highly Cited
2013
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells
Heather J. Lee
,
D. Gallego-Ortega
,
+8 authors
C. Ormandy
Development
2013
Corpus ID: 26857619
Progesterone-RankL paracrine signaling has been proposed as a driver of stem cell expansion in the mammary gland, and Elf5 is…
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Highly Cited
2012
Highly Cited
2012
Elf5 Regulates Mammary Gland Stem/Progenitor Cell Fate by Influencing Notch Signaling
R. Chakrabarti
,
Yong Wei
,
R. Romano
,
C. DeCoste
,
Yibin Kang
,
S. Sinha
Stem Cells
2012
Corpus ID: 22801653
The transcription factor E74‐like factor 5 (Elf5) functions downstream of the prolactin receptor signaling pathway and plays an…
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Highly Cited
2009
Highly Cited
2009
Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5.
Y. Choi
,
R. Chakrabarti
,
Rosalba Escamilla-Hernández
,
S. Sinha
Developmental Biology
2009
Corpus ID: 20982435
Highly Cited
2008
Highly Cited
2008
The Ets transcription factor Elf5 specifies mammary alveolar cell fate.
S. Oakes
,
M. Naylor
,
+10 authors
C. Ormandy
Genes & Development
2008
Corpus ID: 26838978
Hormonal cues regulate mammary development, but the consequent transcriptional changes and cell fate decisions are largely…
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Review
2006
Review
2006
Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium
S. Oakes
,
Heidi N. Hilton
,
C. Ormandy
Breast Cancer Research
2006
Corpus ID: 15252707
Massive tissue remodelling occurs within the mammary gland during pregnancy, resulting in the formation of lobuloalveoli that are…
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Highly Cited
2006
Highly Cited
2006
Socs2 and elf5 mediate prolactin-induced mammary gland development.
Jessica Harris
,
P. Stanford
,
+11 authors
C. Ormandy
Molecular Endocrinology
2006
Corpus ID: 38291027
The proliferative phase of mammary alveolar morphogenesis is initiated during early pregnancy by rising levels of serum prolactin…
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Highly Cited
2006
Highly Cited
2006
Biochemical and NMR Study on the Competition between Proteins SC35, SRp40, and Heterogeneous Nuclear Ribonucleoprotein A1 at the HIV-1 Tat Exon 2 Splicing Site*
Houda Hallay
,
Nicolas Locker
,
L. Ayadi
,
D. Ropers
,
E. Guittet
,
C. Branlant
Journal of Biological Chemistry
2006
Corpus ID: 26102406
The human immunodeficiency virus, type 1, Tat protein plays a key role in virus multiplication. Because of its apoptotic property…
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Highly Cited
2005
Highly Cited
2005
Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation
Jiong Zhou
,
R. Chehab
,
+15 authors
M. Pritchard
EMBO Journal
2005
Corpus ID: 14207683
Elf5 is an epithelial‐specific ETS factor. Embryos with a null mutation in the Elf5 gene died before embryonic day 7.5…
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