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EIF4E2 wt Allele
Known as:
Eukaryotic Translation Initiation Factor 4E Member 2 wt Allele
, EIF4EL3
, 4E-LP
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Human EIF4E2 wild-type allele is located in the vicinity of 2q37.1 and is approximately 33 kb in length. This allele, which encodes eukaryotic…
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National Institutes of Health
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Related topics
Related topics
7 relations
2q37.1
EIF4EL3 protein, human
Genetic Translation Process
Homo sapiens
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Broader (1)
EIF4E2 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
D. Peter
,
Ramona Weber
,
+6 authors
E. Izaurralde
Genes & development
2017
Corpus ID: 28068915
The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5' cap structure…
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2016
2016
Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis.
Luca Valzania
,
H. Ono
,
+5 authors
G. Gargiulo
Developmental biology
2016
Corpus ID: 40590491
2015
2015
The E3 Ubiquitin Ligase ARIH1 Protects against Genotoxic Stress by Initiating a 4EHP-Mediated mRNA Translation Arrest
Louise von Stechow
,
Dimitris Typas
,
+7 authors
E. Danen
Molecular and Cellular Biology
2015
Corpus ID: 11127381
ABSTRACT DNA damage response signaling is crucial for genome maintenance in all organisms and is corrupted in cancer. In an RNA…
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2013
2013
Investigating the Consequences of eIF4E2 (4EHP) Interaction with 4E-Transporter on Its Cellular Distribution in HeLa Cells
D. Kubacka
,
Anastasiia Kamenska
,
Helen E. Broomhead
,
N. Minshall
,
E. Darżynkiewicz
,
N. Standart
PloS one
2013
Corpus ID: 784686
In addition to the canonical eIF4E cap-binding protein, eukaryotes have evolved sequence–related variants with distinct features…
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2012
2012
Quantitative Evaluation of Viability- and Apoptosis-Related Genes in Ascaris suum Eggs under Different Culture-Temperature Conditions
Yong-man Yu
,
You-Hang Cho
,
Y. Youn
,
J. Quan
,
In-Wook Choi
,
Young-Ha Lee
The Korean journal of parasitology
2012
Corpus ID: 14864663
Ascaris suum eggs are inactivated by composting conditions; however, it is difficult to find functional changes in heat-treated A…
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Highly Cited
2007
Highly Cited
2007
ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP.
F. Okumura
,
W. Zou
,
Dong-er Zhang
Genes & development
2007
Corpus ID: 6585856
The expression of the ubiquitin-like molecule ISG15 and protein modification by ISG15 (ISGylation) are strongly activated by…
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Highly Cited
2007
Highly Cited
2007
Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
P. Rosettani
,
S. Knapp
,
M. Vismara
,
L. Rusconi
,
A. Cameron
Journal of molecular biology
2007
Corpus ID: 24610531
Highly Cited
2007
Highly Cited
2007
Weak binding affinity of human 4EHP for mRNA cap analogs.
J. Zuberek
,
D. Kubacka
,
+4 authors
E. Darżynkiewicz
RNA
2007
Corpus ID: 24347573
Ribosome recruitment to the majority of eukaryotic mRNAs is facilitated by the interaction of the cap binding protein, eIF4E…
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2004
2004
Characterizing the interaction of the mammalian eIF4E‐related protein 4EHP with 4E‐BP1
A. Tee
,
Jennifer Tee
,
J. Blenis
FEBS letters
2004
Corpus ID: 32997726
Highly Cited
2003
Highly Cited
2003
Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP
N. Tan
,
H. Ardley
,
G. Scott
,
S. A. Rose
,
A. Markham
,
P. Robinson
FEBS letters
2003
Corpus ID: 25441190
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