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EIF4E2 wt Allele

Known as: Eukaryotic Translation Initiation Factor 4E Member 2 wt Allele, EIF4EL3, 4E-LP 
Human EIF4E2 wild-type allele is located in the vicinity of 2q37.1 and is approximately 33 kb in length. This allele, which encodes eukaryotic… Expand
National Institutes of Health

Related topics

Related topics

7 relations
2q37.1EIF4EL3 protein, humanGenetic Translation ProcessHomo sapiens
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Broader (1)

EIF4E2 gene

Papers overview

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2017
2017
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.
The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5' cap structure… Expand
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2016
2016
Drosophila 4EHP is essential for the larval-pupal transition and required in the prothoracic gland for ecdysone biosynthesis.
Maternal expression of the translational regulator 4EHP (eIF4E-Homologous Protein) has an established role in generating protein… Expand
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2015
2015
The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.
DNA damage response signaling is crucial for genome maintenance in all organisms and is corrupted in cancer. In an RNA… Expand
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2013
2013
Investigating the Consequences of eIF4E2 (4EHP) Interaction with 4E-Transporter on Its Cellular Distribution in HeLa Cells
In addition to the canonical eIF4E cap-binding protein, eukaryotes have evolved sequence–related variants with distinct features… Expand
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2012
2012
Quantitative Evaluation of Viability- and Apoptosis-Related Genes in Ascaris suum Eggs under Different Culture-Temperature Conditions
Ascaris suum eggs are inactivated by composting conditions; however, it is difficult to find functional changes in heat-treated A… Expand
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Highly Cited
2007
Highly Cited
2007
ISG15 modification of the eIF4E cognate 4EHP enhances cap structure-binding activity of 4EHP.
The expression of the ubiquitin-like molecule ISG15 and protein modification by ISG15 (ISGylation) are strongly activated by… Expand
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2007
2007
Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
All eukaryotic cellular mRNAs contain a 5' m(7)GpppN cap. In addition to conferring stability to the mRNA, the cap is required… Expand
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2007
2007
Weak binding affinity of human 4EHP for mRNA cap analogs.
Ribosome recruitment to the majority of eukaryotic mRNAs is facilitated by the interaction of the cap binding protein, eIF4E… Expand
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2004
2004
Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1.
Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) represses translation initiation by binding to eukaryotic initiation… Expand
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2003
2003
Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.
Human homologue of Drosophila ariadne (HHARI) is a RING-IBR-RING domain protein identified through its ability to bind the human… Expand
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