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BACKGROUND: EGFRvIII, a constitutively active tumorigenic EGFR deletion mutation, is linked to poor long-term survival. The… Expand The tumor-specific epidermal growth factor receptor variant III mutation (EGFRvIII) is widely expressed in glioblastoma and thus… Expand Glioblastoma, the most common primary malignant brain tumor, is among the most difficult cancers to treat. Despite the aggressive… Expand Three different synthetic strategies were tested to synthesize EGFRvIII peptide (1), which is a functional variant of the… Expand 2529 Background: Despite multimodality approaches, survival with GBM is dismal. Induction of immune responses to suppress the… Expand SummaryThe type III variant of the epidermal growth factor receptor (EGFRvIII) mutation is present in 20–25% of patients with… Expand EGFRvIII is the type III deletion mutant form of the epidermal growth factor receptor (EGFR) with transforming activity. This… Expand