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EFTUD2 gene

Known as: U5-116KD, elongation factor Tu GTP binding domain containing 2, ELONGATION FACTOR Tu GTP-BINDING DOMAIN-CONTAINING 2 
 
National Institutes of Health

Papers overview

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2017
2017
Abstract Haploinsufficiency of EFTUD2 (Elongation Factor Tu GTP Binding Domain Containing 2) is linked to human mandibulofacial… Expand
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Highly Cited
2016
Highly Cited
2016
U4/U6.U5 tri-snRNP represents a substantial part of the spliceosome before activation. A cryo-electron microscopy structure of… Expand
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2016
2016
Pre-mRNA splicing must occur with high fidelity and efficiency for proper gene expression. The spliceosome uses DExD/H box… Expand
2015
2015
RNA splicing is a fundamental process for protein synthesis. Recent studies have reported that drugs that inhibit splicing have… Expand
Highly Cited
2009
Highly Cited
2009
Brr2 is a DExD/H-box helicase responsible for U4/U6 unwinding during spliceosomal activation. Brr2 contains two helicase-like… Expand
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2009
2009
Conformational changes of snRNAs in the spliceosome required for pre-mRNA splicing are regulated by eight ATPases and one GTPase… Expand
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Highly Cited
2008
Highly Cited
2008
The formation of gametes is a key step in the life cycle of any sexually reproducing organism. In flowering plants, gametes… Expand
2008
2008
Saccharomyces cerevisiae PRP17-null mutants are temperature-sensitive for growth. In vitro splicing with extracts lacking Prp17… Expand
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2006
2006
Snu114 is a U5 snRNP protein essential for pre-mRNA splicing. Based on its homology with the ribosomal translocase EF-G, it is… Expand
Highly Cited
2005
Highly Cited
2005
Snu114 is the only GTPase required for mRNA splicing. As a homolog of elongation factor G, it contains three domains (III–V… Expand
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